Kojic Acid Dipalmitate: Xalkaaga Dabiiciga ah ee Iftiiminta Melasma iyo Baraha Da'da
Kojic Acid Dipalmitate: Xalkaaga Dabiiciga ah ee Iftiiminta Melasma iyo Baraha Da'da
Raadinta maqaar aan cillad lahayn oo dhalaalaysa, dad badani waxay u jeestaan alaabooyin iyo daweyno kala duwan oo daryeelka maqaarka ah. Si kastaba ha ahaatee, helitaanka xal wax ku ool ah oo dabiici ah oo loogu talagalay iftiiminta arrimaha midabka maqaarka, sida melasma iyo dhibcaha da'da, waxay noqon kartaa hawl adag. Nasiib wanaag, waxaa jira walxo awood leh oo kaa caawin kara inaad gaarto natiijooyinka la rabo - Kojic Acid Dipalmitate.
Kojic Acid Dipalmitate, oo sidoo kale loo yaqaan ActiBiso-KDP, waa soo-saarid naafaysay oo kojic acid ah. Kojic acid lafteedu waa walax dabiici ah oo la khamiiriyey lagana nadiifiyey gulukoos ama sukrose iyada oo ay adeegsanayso Aspergillus. Nidaamkeeda caddeynta aasaasiga ah waa in la joojiyo dhaqdhaqaaqa tyrosinase, enzyme ku lug leh soo saarista melanin, taas oo midab siisa maqaarkeena. Waxaa intaa dheer, kojic acid dipalmitate waa walax naadir ah oo caddeeya oo isku mar joojin kara enzymes badan, oo ay ku jiraan N-hydroxyindoleic acid (DHICA) oxidase iyo dihydroxyindole Indole (DHI) polymerization.
Inkasta oo kojic acid ay leedahay sifooyin iftiin leh oo maqaarka ah, waxay u nugul tahay hoos u dhac iyo xasillooni darro marka ay la kulmaan arrimo ay ka mid yihiin iftiinka, kulaylka, iyo ion birta. Intaa waxaa dheer, awoodda ay u leedahay in la nuugo maqaarka ayaa xaddidan. Si looga adkaado caqabadahan, cilmi-baarayaashu waxay soo saareen tiro badan oo ka soo jeeda kojic acid si kor loogu qaado waxtarka walxahan xoogga badan.
Aogubio, oo ah shirkad ku takhasustay soosaarka iyo qaybinta walxaha firfircoon ee dawooyinka, alaabta ceeriin, soosaarka dhirta, iyo nafaqooyinka, ayaa soo bandhigtay wax soo saarkooda cusub - kojic acid dipalmitate, ActiBiso-KDP. Badeecadan kacaanku waxay isku daraysaa sifooyinka ifaya ee maqaarka ee kojic acid oo leh xasiloonida iyo waxqabadka la xoojiyey ee asalkiisa.
Mid ka mid ah sababaha kojic acid dipalmitate uu caan uga noqday suuqa ayaa ah awoodda uu u leeyahay inuu joojiyo dhaqdhaqaaqa tyrosinase, kaas oo mas'uul ka ah soo saarista melanin ee maqaarka. Iyadoo la dhimayo wax soo saarka melanin, kojic acid dipalmitate wuxuu caawiyaa inuu libdho oo iftiimiyo muuqaalka melasma iyo dhibcaha da'da. Intaa waxaa dheer, marka kojic acid dipalmitate lagu daro kuwa ka soo jeeda glucosamine, saameynteeda maqaarka-cadeynta ayaa si aad ah u kordheysa.
Faa'iidooyinka isticmaalka kojic acid dipalmitate waxay ka baxsan yihiin sifooyinka maqaarka ee xoogga leh. Waxa kale oo ay u shaqeysaa sida antioxidant-ka, ka caawinta maqaarka ka ilaalinta waxyeelada oksaydhka ee ay sababaan xagjirrada xorta ah. Tani waxay ka dhigaysaa shay ku habboon alaabta gabowga ka-hortagga, maadaama aanay iftiimin oo keliya meelaha madow ee waxay kaloo gacan ka geysataa ilaalinta maqaarka dhallinyaro iyo caafimaad leh.
Markaad tixgelinayso alaabta daryeelka maqaarka oo ay ku jiraan kojic acid dipalmitate, waa lagama maarmaan in la doorto calaamad sumcad leh sida Aogubio. Iyaga oo khibradooda ku leh soo saarista walxaha firfircoon ee tayada sare leh, alaabta ceeriin, iyo soosaarka dhirta, Aogubio waxay hubisaa waxtarka iyo badbaadada alaabtooda. Ballanqaadkooda ku aaddan buuxinta baahiyaha warshadaha dawooyinka, cuntada, nafaqada, iyo warshadaha qurxinta waxay ka tarjumaysaa sida ay uga go'an tahay bixinta xalal sare oo macaamiisha ah.
Gabagabadii, haddii aad la halgamayso arrimaha midabka maqaarka sida melasma iyo dhibcaha da'da, kojic acid dipalmitate waa xalkaaga dabiiciga ah. Sifooyinkeeda caddeynta xoogga leh, oo ay weheliso saameynteeda antioxidant, ayaa ka dhigaysa doorasho aad u fiican oo lagu gaaro maqaarka dhalaalaya oo xitaa midab leh. Markaad doorato Aogubio's ActiBiso-KDP, waxaad ku kalsoonaan kartaa tayada iyo waxtarka alaabta. Ku macsalaameeya midabka maqaarka oo aan sinnayn oo ku salaam midab dhalaalaya oo kojic acid dipalmitate ah. Qaado awoodda dabeecadda oo daaha ka qaad quruxdaada dhabta ah.
Sharaxaada Alaabta
Kojic acid dipalmitate waa wax laga beddelay derivative kojic acid, taas oo aan ka adkaan xasilloonida iftiinka, kulaylka iyo ion birta ah, laakiin sidoo kale waxay ilaalisaa waxqabadka tyrosinase ee xannibaadda waxayna ka hortagtaa sameynta melanin. Kojic dipalmitate waxay leedahay hanti kiimikaad deggan. Uma beddeli doonto huruud oksaydhdhismeed, ion bir ah, iftiimin iyo kuleyl.
Shaqada
- kojic acid dipalmitate waa nooc ka mid ah horjoogayaasha gaarka ah ee melanin. Waxay ka hortagi kartaa dhaqdhaqaaqa tyrosinase iyada oo la isku dhejiyo ion copper ee unugyada ka dib marka ay gasho unugyada maqaarka. Kojic acid iyo ka-soo-saarkeedu waxay leeyihiin saameyn ka hortag ah oo ka wanaagsan tyrosinase marka loo eego wakiilada kale ee maqaarka.
- kojic acid dipalmitate waxay sidoo kale baabi'in kartaa xagjirnimada xorta ah, waxay xoojisaa dhaqdhaqaaqa unugga waxayna ka dhigi kartaa cuntada mid cusub.
FALANQEYNTA AASAASIGA AH
| Falanqaynta | QAABKA | NATIIJADA |
| Muuqashada | Budada Cad | U hogaansama |
| ur | Sifada | U hogaansama |
| Dhadhamiya | Sifada | U hogaansama |
| Qiimayn | 99% | U hogaansama |
| Falanqaynta Sieve | 100% dhaaf 80 mesh | U hogaansama |
| Khasaare xagga qalajinta | 5% ugu badnaan | 1.02% |
| Sulfated Ash | 5% ugu badnaan | 1.3% |
| Soo saar Walxaha | Ethanol & Biyaha | U hogaansama |
| Birta culus | 5pm ugu badnaan | U hogaansama |
| Sida | 2pm ugu badnaan | U hogaansama |
| Xalalka Haraaga ah | 0.05% ugu badnaan | xun |
| Microbiology | ||
| Wadarta tirada saxanada | 1000/g ugu badnaan | U hogaansama |
| Khamiirka & Caaryada | 100/g ugu badnaan | U hogaansama |
| E.Coli | xun | U hogaansama |
| Salmonella | xun | U hogaansama |
Codsiyada
Daryeelka jirka/wejiga, diyaargarowga gabowga, ilaalinta qoraxda, qoraxda ka dib & is-midabaynta, maqaarka oo caddeeya/ iftiiminta, daawaynta xaaladaha kala duwan ee midabka maqaarka ama xanuunada, tusaale solar lentigenes, melasma, chloasma, nabarro, finan, midabka da'da iyo gobollada kale ee maqaarka hyperpigmented ee maxaliga ah
