I-Kojic Acid Dipalmitate: Isixazululo Sakho Semvelo Sokukhanyisa I-Melasma Nezindawo Zobudala
I-Kojic Acid Dipalmitate: Isixazululo Sakho Semvelo Sokukhanyisa I-Melasma Nezindawo Zobudala
Emzamweni wesikhumba esingenasici nesikhazimulayo, abantu abaningi baphendukela emikhiqizweni ehlukahlukene ye-skincare kanye nokwelashwa. Kodwa-ke, ukuthola isisombululo esisebenzayo nesemvelo sezinkinga zokukhanya kwesikhumba, njenge-melasma namabala obudala, kungaba umsebenzi oyinselele. Ngenhlanhla, kunesithako esinamandla esingakusiza ukuthi uzuze imiphumela oyifunayo - i-Kojic Acid Dipalmitate.
I-Kojic Acid Dipalmitate, eyaziwa nangokuthi i-ActiBiso-KDP, iphuma e-diesterized ye-kojic acid. I-Kojic acid ngokwayo iyisithako semvelo esivutshelwa futhi sihlanzwe ku-glucose noma i-sucrose ngaphansi kwesenzo se-Aspergillus. Indlela yayo eyinhloko yokwenza mhlophe iwukuvimbela umsebenzi we-tyrosinase, i-enzyme ehilelekile ekukhiqizeni i-melanin, enikeza umbala esikhumbeni sethu. Ngaphezu kwalokho, i-kojic acid dipalmitate iyi-ejenti emhlophe eyodwa engavamile engavimbela ngesikhathi esisodwa ama-enzyme amaningi, okuhlanganisa i-N-hydroxyindoleic acid (DHICA) oxidase kanye ne-dihydroxyindole Indole (DHI) polymerization.
Nakuba i-kojic acid inezici ezikhanyisa isikhumba ezimangalisayo, isengozini yokuwohloka nokungaqini lapho ibhekene nezinto ezifana nokukhanya, ukushisa, nama-ion ensimbi. Ngaphezu kwalokho, ikhono layo lokumuncwa isikhumba lilinganiselwe. Ukuze banqobe lezi zinselele, abacwaningi baye basungula izinto eziningi eziphuma ku-kojic acid ukuze bathuthukise ukusebenza kwalesi sithako esinamandla.
I-Aogubio, inkampani eyisipesheli ekukhiqizeni nasekusabalaliseni izinto ezisebenza ekhemisi, izinto ezingavuthiwe, okukhishwe kwezitshalo, nama-nutraceuticals, yethule umkhiqizo wayo omusha - i-kojic acid dipalmitate, i-ActiBiso-KDP. Lo mkhiqizo wenguquko uhlanganisa izakhiwo ezikhazimulayo zesikhumba ze-kojic acid nokuzinza nokusebenza okuthuthukisiwe kokuphuma kwayo.
Esinye sezizathu ezenza ukuthi i-kojic acid dipalmitate ithole ukuthandwa emakethe amandla ayo okuvimbela umsebenzi we-tyrosinase, obhekele ukukhiqizwa kwe-melanin esikhumbeni. Ngokunciphisa ukukhiqizwa kwe-melanin, i-kojic acid dipalmitate isiza ukufiphala futhi ikhanyise ukubukeka kwe-melasma namachashaza obudala. Ukwengeza, lapho i-kojic acid dipalmitate ihlanganiswa nokuphuma kokuphuma ku-glucosamine, umphumela wayo wokwenza mhlophe kwesikhumba uyanda kakhulu.
Izinzuzo zokusebenzisa i-kojic acid dipalmitate zidlula izici zayo ezikhanyisa isikhumba. Isebenza futhi njenge-antioxidant, isiza ukuvikela isikhumba emonakalweni we-oxidative obangelwa ama-radicals mahhala. Lokhu kuyenza ibe isithako esikahle emikhiqizweni elwa nokuguga, ngoba ayigcini nje ngokukhanyisa amabala amnyama kodwa isiza nasekugcineni isikhumba esibukeka sisemusha futhi sinempilo.
Uma ucubungula umkhiqizo we-skincare oqukethe i-kojic acid dipalmitate, kubalulekile ukukhetha uhlobo olunegama elihle njenge-Aogubio. Ngolwazi lwabo ekukhiqizeni izinto ezisebenzayo zekhwalithi ephezulu, izinto ezingavuthiwe, nezingcaphuno zezitshalo, i-Aogubio iqinisekisa ukusebenza kahle nokuphepha kwemikhiqizo yabo. Ukuzinikela kwabo ekuhlangabezaneni nezidingo zezimboni zemithi, zokudla, ezomsoco, nezimonyo kukhombisa ukuzinikela kwabo ekunikezeni izixazululo ezingcono kakhulu kubathengi.
Sengiphetha, uma ulwa nezinkinga zokushintsha umbala wesikhumba njenge-melasma namachashaza obudala, i-kojic acid dipalmitate iyisixazululo sakho semvelo. Izakhiwo zayo ezimhlophe ezinamandla, ezihambisana nemiphumela yayo yokulwa ne-antioxidant, ziyenza ibe yisinqumo esihle kakhulu sokuthola isikhumba esikhanyayo nesilingana kakhulu. Ngokukhetha i-ActiBiso-KDP ye-Aogubio, ungaqiniseka ngekhwalithi nokusebenza komkhiqizo. Valelisa esikhumbeni esingalingani futhi sawubona ibala elikhazimulayo eline-kojic acid dipalmitate. Yamukela amandla emvelo futhi wembule ubuhle bakho bangempela.
Incazelo Yemikhiqizo
I-Kojic acid dipalmitate i-modified kojic acid derivative, engagcini nje ngokunqoba ukuntengantenga kokukhanya, ukushisa kanye ne-iron eyinsimbi, kodwa futhi igcina umsebenzi ovimbelayo we-tyrosinase futhi ivimbele ukwakheka kwe-melanin. I-Kojic dipalmitate ingumnikazi wendawo yamakhemikhali ezinzile. Ngeke ijike ibe phuzi uma isetshenziselwa i-oxidation, i-metallic ion, ukukhanya nokushisa.
Umsebenzi
- i-kojic acid dipalmitate iwuhlobo lwesivimbeli esikhethekile se-melanin. Ingavimbela umsebenzi we-tyrosinase ngokuhlanganiswa ne-ion yethusi kumaseli ngemva kokungena kumaseli esikhumba. I-Kojic acid nokuphuma kwayo kunomphumela ongcono wokuvimbela i-tyrosinase kunanoma iyiphi enye i-ejenti emhlophe yesikhumba.
- I-kojic acid dipalmitate ingaphinda iqede i-radical yamahhala, iqinise ukusebenza kwamaseli futhi igcine ukudla kukusha.
UKUHLAZIYWA OKUSISEKELO
| UHLAZIYO | INKCAZO | IMIPHUMELA |
| Ukubukeka | Impushana Emhlophe | Iyahambisana |
| Iphunga | Isici | Iyahambisana |
| Kunambithile | Isici | Iyahambisana |
| Isivivinyo | 99% | Iyahambisana |
| Sieve Analysis | I-100% idlula i-80 mesh | Iyahambisana |
| Ukulahlekelwa Ekumisweni | 5% Ubukhulu. | 1.02% |
| Umlotha one-sulphate | 5% Ubukhulu. | 1.3% |
| Khipha i-Solvent | I-Ethanol Namanzi | Iyahambisana |
| Insimbi Enzima | 5 ppm Max | Iyahambisana |
| Njengoba | 2ppm Max | Iyahambisana |
| Izincibilikisi Ezisele | 0.05% Ubukhulu. | Okubi |
| I-Microbiology | ||
| Inani Lepuleti Eliphelele | 1000/g Ubukhulu | Iyahambisana |
| Imvubelo & Isikhunta | 100/g Ubukhulu | Iyahambisana |
| E.Coli | Okubi | Iyahambisana |
| I-Salmonella | Okubi | Iyahambisana |
Izinhlelo zokusebenza
Ama-toner okunakekela umzimba/ubuso, izinto zokulwa nokuguga, ukuvikela ilanga, ngemva kokushona kwelanga nokuzishuka, ukucwenga kwesikhumba/ukukhanya, ukwelapha izimo ezihlukahlukene zesikhumba ezishintsha umbala obala noma iziyaluyalu, isb ama-solar lentigene, i-melasma, i-chloasma, izibazi, amabala, ubudala be-pigment nezinye izindawo zesikhumba ezinombala ogqamile
