Soo Bandhigidda Xaqiiqda Ka Danbaysa Kojic Acid Dipalmitate iyo Waxtarkeeda

Soo Bandhigidda Xaqiiqda Ka Danbaysa Kojic Acid Dipalmitate iyo Waxtarkeeda

Kojic acid dipalmitate, oo sidoo kale loo yaqaan 2-Palmitoylmethyl-5-palmitoyl-pyrone, waa dufan-soluble ka soo jeeda kojic acid. Waa walxo firfircoon oo caan ka helay warshadaha qurxinta sababtoo ah maqaarka-iftiiminta iyo sifooyinka melanin-ka. Maqaalkani, waxaanu sahamin doonaa waxtarka kojic acid dipalmitate waxaanan iftiimin doonaa faa'iidooyinka suurtagalka ah ee maqaarka.

Aogubio, shirkad ku takhasustay soo saarista iyo qaybinta maaddooyinka farmasiga ahaan firfircoon, alaabta ceeriin, dhirta laga soo saaro, iyo nafaqeeyayaalka, ayaa hormood u ahayd soo saaraha kojic acid dipalmitate. Aogubio waxa ay isku dhistay dawooyinka, cuntada, nafaqeynta, iyo warshadaha qurxinta iyada oo bixisa alaabo tayo sare leh oo loogu talagalay isticmaalka aadanaha. Khibraddooda iyo aqoontooda, Aogubio waxa uu si guul leh ugu dabaqay kojic acid dipalmitate soo saarista waxyaabaha la isku qurxiyo, taas oo ka dhigaysa il la aamini karo ee walaxdan xoogga leh.

Kojic acid, horudhaca kojic acid dipalmitate, waa walax ay soo saaraan fangaska dhowr ah sida Aspergillus oryzae, Aspergillus parasiticus, iyo Aspergillus flavus. Waxa kale oo laga helaa cuntooyinka khamiirka leh sida suugo soy, koollada soybean, iyo khamriga. Jabbaanku waxay qarniyo badan u adeegsanayeen kojic acid soo saarista khamriga bariiska ee Japan, oo loo yaqaan "jiu koji." Japan ayaa weli ah soo saaraha ugu weyn ee kojic acid caalamka tan iyo 1970-meeyadii.

Kala duwanaanshaha kojic acid dipalmitate waxay ku jirtaa xasilloonida iyo waxtarkeeda marka la barbar dhigo kojic acid dhaqameed. Kojic acid waxay caan ku tahay xasillooni darrada iftiinka, kuleylka, iyo ion birta, taas oo wax u dhimi karta waxtarkeeda. Si kastaba ha noqotee, iyada oo la soo bandhigayo kojic acid dipalmitate, cilladahan waa laga gudbay. Nadiifinta kooxda hydroxyl ee firfircoon ee qaabdhismeedka molecular ee kojic acid dipalmitate waxay ka ilaalisaa samaynta curaarta hydrogen ee maaddooyinka kale ee la isku qurxiyo. Tani waxay hubineysaa in shaqeynta waxyaabaha kale ee lagu daro aan la saameynin, taasoo u oggolaaneysa wadashaqeyn wanaagsan oo lala yeesho alaabta kale ee cayriin ee qurxinta.

Mid ka mid ah faa'iidooyinka ugu muhiimsan ee kojic acid dipalmitate waa awoodda ay u leedahay inay joojiso sameynta melanin. Melanin ayaa mas'uul ka ah madoobaynta maqaarka, iyo soo saaristiisa xad dhaafka ah waxay u horseedi kartaa midab buluug ah iyo midabka maqaarka oo aan sinnayn. Iyadoo la joojinayo tyrosinase, enzyme ku lug leh soo saarista melanin, kojic acid dipalmitate waxay caawisaa in ay iftiimiso maqaarka oo ay yareyso muuqaalka dhibco madow iyo ciladaha. Habka gaarka ah ee kojic acid dipalmitate waxay hubisaa in waxqabadkeeda ugu fiican la ilaaliyo, taasoo bixisa natiijooyin wax ku ool ah maqaarka maqaarka.

Intaa waxaa dheer, kojic acid dipalmitate waxay bixisaa guryaha qoyaanka, taas oo ka dhigaysa shey ku habboon qurxinta. La jaanqaadkeeda alaabta ceeriin ee la isku qurxiyo waxay u oggolaaneysaa inay si isku mid ah u shaqeyso, oo u geyso fuuq-celinta maqaarka iyada oo aan waxyeello loo geysan waxtarka waxyaabaha kale ee lagu daro. Tani waxay ka dhigaysaa kojic acid dipalmitate walxo badan oo aan kaliya iftiimin maqaarka laakiin sidoo kale nafaqeeya oo fuuqbixiya, kor u qaada midab caafimaad leh oo dhalaalaya.

Gebogebadii, kojic acid dipalmitate waa walax awood leh oo ka mid ah warshadaha qurxinta, oo loo yaqaan maqaarka-iftiiminta iyo sifooyinka melanin-ka-hortagga. Aogubio, oo ah shirkad sumcad leh oo ku takhasustay wax soo saarka iyo qaybinta walxaha firfircoon iyo alaabta ceeriin, ayaa si guul leh ugu dartay kojic acid dipalmitate alaabtooda qurxinta. Iyada oo ay xasilloon tahay, waxtarkeeda, iyo guryaha qoyaanka, kojic acid dipalmitate waxay bixisaa xal weyn oo loogu talagalay kuwa doonaya inay hagaajiyaan muuqaalkooda maqaarkooda oo ay gaaraan midab ka sii badan.