I-N-Acetylcysteine Ingasiza Kanjani Ukulwa Nokucindezeleka Kwe-Oxidative
I-N-Acetylcysteine (NAC) iyinhlanganisela evame ukutholakala ngendlela yama-capsules noma i-powder, futhi izinzuzo zayo ezingase zibe khona ekulweni nokucindezeleka okwenziwe nge-oxidative ziye zathola ukunakwa okuphawulekayo eminyakeni yamuva. Ukucindezeleka kwe-oxidative kwenzeka lapho kunokungalingani phakathi kokukhiqizwa kwama-radicals mahhala kanye nekhono lomzimba lokubhekana nemiphumela yawo eyingozi. Lesi sihloko sihlose ukuhlola ukuthi i-N-Acetylcysteine ingasiza kanjani ukulwa nengcindezi ye-oxidative futhi ikhuthaze ukuphila kahle okuphelele.
I-N-Acetylcysteine ingumanduleli we-glutathione, i-antioxidant enamandla ekhiqizwa ngokwemvelo imizimba yethu. I-Glutathione idlala indima ebalulekile ekuvikeleni amaseli emonakalweni we-oxidative obangelwa ama-radicals mahhala. Kodwa-ke, izici ezihlukahlukene ezifana nokudla okungenamsoco, ukungcola kwemvelo, nokucindezeleka kunganciphisa amazinga e-glutathione, kubeke engcupheni ukuzivikela komzimba ekucindezelekeni kwe-oxidative. Yilapho i-N-Acetylcysteine supplementation ingaba nenzuzo.
Ngokuhlinzeka nge-cysteine, ingxenye ebalulekile ye-glutathione, i-N-Acetylcysteine isiza ukuthuthukisa ikhono lomzimba lokuhlanganisa nokuvuselela i-glutathione. Lo msebenzi we-antioxidant usiza ukuqeda ama-radicals mahhala, unciphise ingcindezi ye-oxidative futhi uvimbele ukulimala kwamaselula. Ngenxa yalokho, i-N-Acetylcysteine ibonise imiphumela ethembisayo ezimweni zezempilo ezihlukahlukene ezihambisana nokucindezeleka okwenziwe nge-oxidative, okuhlanganisa izifo zesibindi namaphaphu, ukuphazamiseka kwenhliziyo, kanye nokuphazamiseka kwezinzwa njenge-Alzheimer's and Parkinson's disease.
Ngaphezu kwalokho, i-N-Acetylcysteine ifundwe kabanzi ngenxa yamandla ayo okuvikela emiphumeleni eyingozi yobuthi bemvelo. Isebenza njenge-ejenti enamandla yokukhipha ubuthi ngokubopha izinsimbi ezisindayo njenge-mercury nomthofu, isiza ekukhishweni kwazo emzimbeni. Leli khono lenza i-N-Acetylcysteine ibe yinzuzo ikakhulukazi kubantu abachayeke emazingeni aphezulu okungcola kwemvelo noma labo abathola ukwelashwa okuthile, okufana nokwelashwa ngamakhemikhali.
Ngaphandle kwezakhiwo zayo ze-antioxidant kanye ne-detoxifying, i-N-Acetylcysteine iphinde yabonisa imiphumela ephikisana nokuvuvukala. Ukuvuvukala okungapheli kuhlobene eduze nokucindezeleka okwenziwe nge-oxidative futhi kuyisici esivamile esiyisisekelo ezifweni eziningi ezingapheli. Ngokunciphisa izimpawu zokuvuvukala kanye nokulimala kwe-oxidative, i-N-Acetylcysteine isiza ekudambiseni ukuvuvukala, okungase kube ngcono izimpawu ezimeni ezifana nesifo samathambo kanye nesifo se-chronic obstructive pulmonary (COPD).
Ngaphezu kwalokho, i-N-Acetylcysteine ibonise isithembiso ekugcineni impilo yokuphefumula. Kungasiza ukucasha futhi kuxege amafinyila, kube lula ukuwasula emigudwini yomoya. Lokhu kwenza kube isengezo esibalulekile ekulawuleni izimo zokuphefumula njenge-bronchitis engapheli kanye ne-cystic fibrosis. Ukwengeza, ucwaningo luye lwabonisa ukuthi i-N-Acetylcysteine supplementation ingathuthukisa ukusebenza kwamaphaphu futhi inciphise ukukhushulwa kwabantu abane-COPD.
Nakuba i-N-Acetylcysteine ngokuvamile ibhekwa njengephephile, kubalulekile ukubonana nochwepheshe bezempilo ngaphambi kokuqala noma yiluphi uhlobo olusha lwemithi yokwelapha. Bangakunikeza iseluleko somuntu siqu ngokusekelwe esimweni sakho sezempilo nanoma yimiphi imithi okungenzeka ukuthi uyayidla. Imiphumela engemihle evamile njengokucanuzela kwenhliziyo, ukuhlanza, nobuhlungu besisu ayivamile kodwa ingenzeka kwabanye abantu. Kubalulekile futhi ukuqaphela ukuthi i-N-Acetylcysteine ingase ihlanganyele nemithi ethile, njenge-nitroglycerin, futhi ukuqapha kufanele kusetshenziswe lapho kuhlanganiswe.
Ekuphetheni, i-N-Acetylcysteine supplementation ngendlela yama-capsules noma i-powder inganikeza izinzuzo eziningi ekulweni nokucindezeleka okwenziwe nge-oxidative nokukhuthaza impilo yonke. I-antioxidant, i-detoxifying, anti-inflammatory, kanye nezakhiwo zayo ezisekela ukuphefumula ziyenza ibe isengezo esisebenza ngezindlela eziningi ezimweni zezempilo ezahlukahlukene. Kodwa-ke, kubalulekile ukubonana nochwepheshe bezempilo ngaphambi kokuqala i-N-Acetylcysteine supplementation ukuze uqinisekise ukufaneleka kwayo ezidingweni zakho ezithile.
Incazelo Yomkhiqizo
I-N-acetyl cysteine (NAC) ivela ku-amino acid L-cysteine. Ama-amino acid ayizingqimba zokwakha amaprotheni. I-NAC inokusetshenziswa okuningi futhi iwumuthi ogunyazwe yi-FDA.
I-N-acetyl cysteine i-antioxidant engase ibambe iqhaza ekuvimbeleni umdlavuza. Njengomuthi, usetshenziswa abahlinzeki bezempilo ukwelapha ubuthi be-acetaminophen (Tylenol). Isebenza ngokubopha izinhlobo ezinobuthi ze-acetaminophen ezakheka esibindini.
Abantu bavame ukusebenzisa i-N-acetyl cysteine ukukhwehlela nezinye izimo zamaphaphu. Ibuye isetshenziselwe umkhuhlane, iso elomile, nezinye izimo eziningi, kodwa abukho ubufakazi obuhle besayensi obusekela okuningi kwalokhu kusetshenziswa. Abukho futhi ubufakazi obuhle bokusekela ukusebenzisa i-N-acetyl cysteine ye-COVID-19.
I-N-Acetyl-L-Cysteine iyi-amino acid, ingashintshwa isuka emzimbeni we-methionine, i-cystine ingaguqulwa nomunye nomunye. I-N-Acetyl-l-cysteine ingasetshenziswa njenge-ejenti ye-mucilagenic. Ifanele ukuvinjelwa kokuphefumula okubangelwa inani elikhulu lokuvinjelwa kwe-phlegm. Ngaphezu kwalokho, ingasetshenziswa futhi ukuqeda ubuthi obunobuthi be-acetaminophen.
Umsebenzi
I-N-Acetyl-L-Cysteine iyi-amino acid, ingashintshwa isuka emzimbeni we-methionine, i-cystine ingaguqulwa nomunye nomunye. I-N-Acetyl-l-cysteine ingasetshenziswa njenge-ejenti ye-mucilagenic. Ifanele ukuvinjelwa kokuphefumula okubangelwa inani elikhulu lokuvinjelwa kwe-phlegm. Ngaphezu kwalokho, ingasetshenziswa futhi ukuqeda ubuthi obunobuthi be-acetaminophen.
