Mgbakwunye mgbochi ịka nká 99% Pyrroloquinoline Quinone PQQ ntụ ntụ
Nkọwa ngwaahịa
Pyrroloquinoline Quinone (PQQ) bụ obere molekul quinone nwere vitamin dị ka Dihexa (PNB-0408) ntụ ntụ.Ngwakọta ahụ bụ onye na-ahụ maka redox nwere ike na-agbakọ dị ka antioxidant.Ya mere, ọ bụ nnọọ kwụsiri ike na pharmacologically dị ịrịba ama na ọgwụgwọ nke neurodegeneration.
Ọtụtụ nchọpụta ụlọ ọgwụ na-akwado pyrroloquinoline quinone (PQQ) dị ike karịa vitamin C antioxidants dị ka ascorbic acid na epicatechin.
Nke a ịnweta bụ ndammana synthesized na dị iche iche osisi.Ụfọdụ n'ime nri nri Pyrroloquinoline quinone gụnyere pọpọ, mkpụrụ kiwi, tii tii, soybean, pasili, na ose green.Ọ bụ ezie na ogige ahụ nwere ike iyi ihe na-edozi ahụ adịghị mkpa na nri mmadụ, ọnụnọ ya na usoro anụ ahụ na-egosi na ọ nwere uru ahụike pụtara ìhè.
Pyrroloquinoline quinone na-erite uru ọrụ mitochondrial.Ịrụ ọrụ nke akụkụ ahụ ndị a na-eme ka ike sel dị mma, gụnyere uto cellular na nlanarị.
Asambodo nyocha
| Ihe | Nkọwapụta | Nsonaazụ |
| Ọdịdị | ntụ ntụ na-acha uhie uhie uhie | Na-akwado |
| Detụ ire | Nnu | Na-akwado |
| njirimara | Egwuregwu dị mma yana ọkọlọtọ | Na-akwado |
| Assay (ndabere akọrọ) | ≥98% | 98.50% |
| Ọnwụ na ihicha | ≤12% | 4.70% |
| Nha urughuru (site na ntupu 20) | ≥99% | > 99.0% |
| Ash | ≤1.0% | 0.30% |
| Ọla dị arọ (dị ka Pb) | ≤10PPM | Na-akwado |
| Arsenic (As) | ≤1.0PPM | Achọpụtaghị |
| Cadmium (Cd) | ≤1.0PPM | 0.2PPM |
| Ndu (Pb) | ≤0.5PPM | Achọpụtaghị |
| Mercury (Hg) | ≤0.1PPM | Achọpụtaghị |
| Ihe mgbaze fọdụrụ (Ethanol,%) | ≤0.5 | 0.10% |
| Ọnụọgụ Plate Aerobic | ≤100cfu/g | Na-akwado |
| Yist&Ebu | ≤100cfu/g | Na-akwado |
| E.coli | Na-adịghị mma/25g | Ihe ọjọọ |
| Salmonella | Na-adịghị mma/25g | Ihe ọjọọ |
Kedu ka Pyrroloquinoline quinone (PQQ) si arụ ọrụ?
Usoro nke PQQ na-eme ka ọ bụrụ nke Dihexa (PNB-0408) ntụ ntụ.Ngwaahịa a na-ejikọ ma na-agbanwe ọrụ nke quinoproteins n'ime ahụ mmadụ.Ọ bụ antioxidant dị ike, nke na-arụ ọrụ iji kpochapụ radicals free n'ime sel.Ngwakọta ahụ dị 100x dị irè karịa vitamin C.
N'ime ọmụmụ ihe izizi na ụdị murine, Pyrroloquinoline quinone ntụ ntụ (72909-34-3) ọgwụ mbufụt na-akpali mmepụta nke mitochondria maka ịrụ ọrụ kacha mma nke cell.Ngwakọta a na-emekọrịta ihe na ụzọ mgbaàmà cell, nke na-eme ka biogenesis mitochondrial dị elu.
Ngosipụta na Pyrroloquinoline quinone disodium nnu na-eme ka mmefu ike dịkwuo mma ma na-ebelata triglycerides plasma.Ọ na-ebelata ischemia obi ma na-ebelata mfu neuronal na ọnwụ cell.
Uru 5 nke ị were Pyrroloquinoline quinone (PQQ)
- I. Na-eme ka ọrụ Mitochondrial dịkwuo mma
Mitochondrial dysfunction bụ isi ihe na-akpata ọtụtụ ọrịa neurodegenerative dị ka Alzheimer, multiple sclerosis, ọrịa Parkinson, na ọrịa cancer.
Ya mere, ọ bụ ihe doro anya ma dị irè iji kwalite arụmọrụ nke mitochondria kama ịdo dọkịta ihe mgbaàmà nke ọrịa ndị a.Inweta mgbakwunye PQQ Alzheimer ga-eme ka ọgbọ mitochondria ọkụ.N'ime afọ ndị gafeworonụ, ihe mgbakwunye nri na ọgwụ ọgwụ egosila na ha na-ekwe nkwa maka ịkwalite njupụta na ịdị irè nke akụkụ ahụ cell a.Otu n'ime ihe ndị a rụpụtara nke ọma bụ nchọpụta pyrroloquinoline quinone.
Na mgbakwunye, ọ na-ebelata nrụgide oxidative n'ime anụ ahụ cellular.Ya mere, PQQ nwere ike ịbụ ogige mgbochi ịka nká nke dị jụụ, nke na-eme ka ọgụgụ isi na ebe nchekwa dịkwuo mma, ebe ọ na-atụgharị nsogbu nke neuronal nke jikọtara ya na senescence.
- II.Na-eme ka ihe na-eto eto akwara (NGF)
Mgbe PQQ na-emekọrịta ihe na ụzọ cellular, ọ na-ahapụ mgbe niile mmetụta dị mma na ihe uto akwara site n'ịkwalite ọganihu ha.Ọ na-ahụ maka nlanarị na mmepe nke sel neuronal.N'ihi ya, enwere nchebe nke neurons na mmepụta nke irighiri akwara na anụ ahụ cranial.Ya mere, anyị nwere ike ikwu na pyrroloquinoline quinone disodium nnu na-eme ka ọrụ ụbụrụ dịkwuo elu.
Ndị dọkịta na-ejikọta NGF dysregulation na ọrịa Alzheimer.Ya mere, Pyrroloquinoline quinone nwere ike ịbụ ezigbo ọgwụ mgbochi maka ọnọdụ afọ a.
- III.Na-egbochi nrụgide Oxidative
Nchegbu oxidative bụ maka nnukwu ọrịa na-adịghị ala ala dịka ọrịa neurodegenerative na ụfọdụ carcinomas.
PQQ na-edobe iji belata mmebi oxidative nke na-esite na radicals free, ma na-akwalite metabolism nke ume, n'ihi ihe ndị antioxidant ya.Pyrroloquinoline quinone disodium na-ebelata ọkwa nke IL-6 na C-Reactive Protein, nke na-enye aka nrịbama nke mbufụt.
- IV.Nchekwa Neuro
Pyrroloquinoline quinone disodium nnu na-eme ka ọrụ ụbụrụ dị elu, cognition, ebe nchekwa, na nlebara anya.Ịrụ ọrụ nke mitochondrial na-ekwe nkwa ibi ndụ dị mma nke na-enweghị ọrịa neurodegenerative.
N'ime ọmụmụ ihe gbasara ụlọ ọgwụ na-agụnye isiokwu 41 ndị agadi, ndị ọkà mmụta ahụ kwadoro na PQQ nwere ike ịkwalite cognition, gbochie nkwụsị ncheta, ma melite nlebara anya.
- V. Na-akwalite metabolism lipid
N'ime ọmụmụ ihe izizi, ụdị murine nwere ụkọ Pyrroloquinoline quinone disodium nwere ọnụego metabolic dị ala yana ọkwa dị elu nke triglycerides.N'aka nke ọzọ, oke ndị nwere ọkwa Pyrroloquinoline quinone nkịtị nwere ọkwa dị mma nke cholesterol, triglycerides, ọbara mgbali elu na adiposity.
E wezụga ịbụ neuroprotective, PQQ bụkwa cardioprotective.Ndị mmadụ n'otu n'otu na-ewere ihe ahụ adịchaghị enwe mmerụ ahụ nke obi n'ihi ischemia ma ọ bụ reperfusion.
Uru ndị ọzọ a ma ama Pyrroloquinoline quinone bụ nkwalite ụra na mmụba nke ọmụmụ na ọmụmụ.
Kedu nri nwere Pyrroloquinoline quinone (PQQ)?
- Soybean fermented (natto).Isi mmalite nri Pyrroloquinoline quinone nwere ọdịnaya kachasị elu nke PQQ, nke bụ 61 ng/g.
- Green tii
- Ose griin
- Kiwi mkpụrụ
- Pọọpọ
- Agwa agwa (tofu)
- Akwụkwọ nri
- Coke
- Pasili
- Oolong
ihe ọkụkụ egosila na ọ bụ isi iyi nke Pyrroloquinoline quinone (PQQ).Ọ bụ ezie na ihe oriri anụmanụ dị ka àkwá na mmiri ara ehi dabara n'ụdị a, ụfọdụ ndị ọkà mmụta sayensị ewepụwo ha dị ka ịkọ nkọ.Usoro nchọpụta a na-ajụ ajụjụ ebe ọ bụ na mkpụrụ ndụ mammalian enweghị ike ịmepụta Pyrroloquinoline quinone.Ndị ọkà mmụta na-eche na ọdịnaya PQQ dị na anụ ahụ mmadụ sitere na nri ma ọ bụ mmepụta nje bacteria.
