Gura Nicotinamide Mononucleotide Yinyongera - Kongera imikorere ya selile

NMN (Nicotinamide mononucleotide): Izina ryuzuye ni "β-nicotinamide mononucleotide", ni bisanzwe bisanzwe nucleotide ikora ibinyabuzima. Hariho uburyo bubiri budasanzwe bwa NMN, α na β; β isomer nuburyo bukora bwa NMN hamwe nuburemere bwa molekile ya 334.221 g / mol. Kubera ko nicotinamide ari vitamine B3, Ifu ya NMN iri mu cyiciro cya vitamine B. Ifite uruhare runini mubikorwa bya biohimiki yumubiri wumuntu kandi bifitanye isano rya bugufi nubudahangarwa na metabolism.

IbyokuryaNikotinamide Mononucleotide(NMN na β-NMN) ni nucleotide ikomoka kuri ribose na nicotinamide. Ubushakashatsi bwigihe kirekire bwerekana ko NMN ishobora kugabanya umuvuduko wa physiologique mugusaza.

NMN Ibiribwa Byakozwe na aogubio ni ibya Vitamine B, bigira uruhare muri metabolism mumubiri.

NMN Ibiribwa birashobora gukoreshwa nkibiryo nimirire yabantu, bigatera imikurire kandi bigashimangira ubudahangarwa.

Ibintu biranga umubiri wumuntu nabyo bikungahaye ku mbuto n'imboga zimwe. Mu mubiri w'umuntu,nicotinamide mononucleotideni ibanziriza cyane ya NAD +, kandi imikorere yayo igaragarira muri NAD +. NAD + nayo yitwa Coenzyme I, kandi izina ryayo ryuzuye ni nicotinamide adenine dinucleotide. Irahari muri buri selile kandi igira uruhare mubihumbi. Muburyo butandukanye bwimikorere ya selile, nicotinamide adenine dinucleotide (NAD) molekile igira uruhare runini kandi ninkunga ikomeye yingirabuzimafatizo kugirango ibungabunge ubuzima.

Kugabanuka kwa NAD muburyo bwo gusaza bifatwa nkimpamvu nyamukuru itera indwara nubumuga, nko kutumva no kutabona, imikorere mibi ya cognitive na moteri, kubura ubudahangarwa bw'umubiri, arthritis, indwara ziterwa na metabolike n'indwara z'umutima-damura ziterwa no kudashyira mu gaciro kwa autoimmune. Kubwibyo, kuzuza Beta NMN byongera NAD + mumubiri, bityo bikadindiza, bigatera imbere, kandi bikarinda fenotipa zitandukanye zijyanye no gusaza, cyangwa indwara ziterwa na metabolike ziterwa nimyaka, indwara zumusemburo, nibindi.

Uburyo bwo kubyaza umusaruro

	Semi-Fermentation Gukomatanya Niacinamide ribose chloride mbere, hanyuma ikabyara muri NMN Nicotinamide Mononucleotide na fermentation. Ibibi:Enzyme proteine ​​yangiza umubiri wumuntu izakorwa mugihe cyumusaruro, kandi umwanda wa enzyme protein ugomba kugenzurwa cyane. Ibyiza:Ubuziranenge buri hejuru gato kurenza ubwiza bwuburyo bwubukorikori.
Synthetic Aogu NMN Ibyiciro byibiryo byahinduwe muburyo bwa chimique kuva itangira kugeza irangiye Ibibi:Imyanda ya genotoxique ikorwa kandi igasigara. Ibyiza:Umwanda wose urasobanutse neza iyo urebye, Birashobora kugeragezwa na HPLC.

Itandukaniro rya NMN NAD NR

NAD + ni coenzyme y'ingenzi muri mitochondriya ya okiside ya aerobic na metabolisme ya tricarboxylic aside cycle kugirango itange ingufu za molekile ATP, kuburyo ubwoko butatu bwintungamubiri zabonetse mumubiri wumuntu: isukari, ibinure na proteyine, bihinduka imbaraga zisabwa na umubiri w'umuntu. Nyamara, kubera uburemere bwa molekuline nini, biragoye ko NAD + yinjira muri selile hanyuma ikinjira muri selile, ntishobora rero gufatwa neza.

Byinshi mu kanwa NR ntabwo bihinduweNMN, ariko yinjiye muri NAM, kunanirwa kurenga kubuza inzitizi igabanya igipimo cya NAMPT munzira ya salvage synthesis, kandi ubushobozi bwo kuzuza NAD + ni buke.

AoguNMN Nicotinamide Mononucleotidekurenga icyuho cya enzyme igabanya igipimo cya NAMPT kandi irashobora kuzuza vuba NAD + mumubiri, nuburyo bwiza kandi bwiza bwo kuzuza. NMN irashobora kwinjira vuba mumubiri muminota 10, hanyuma nyuma yiminota 30 ikinjizwa ningingo zumubiri igahinduka NAD +, ishobora kuzuza vuba NAD + mumubiri.

Aogu Biotech, NMN yabigize umwuga mu Bushinwa, itanga 99% min isuku, ushaka kumenya byinshi? Menyesha Aogu Biotech mugihe cyambere cyawe.

Intangiriro y'Ikigo

Aogubio Yinzobere mu gukuramo ibimera imyaka 10. Nkuruganda rukora ibimera byumwuga mubushinwa, dusezeranya gutanga ibicuruzwa byiza kandi bifite igiciro cyiza kubakiriya bacu bubahwa.

Ibicuruzwa byuruganda rwacu birimo ifu yikuramo ibimera, ibikoresho byo kwisiga, inyongeramusaruro, ifu y ibihumyo kama, ifu yimbuto, aside Amio na vitamine nibindi.

Twandikire: Amahirwe Wang:+8618700474175 丨 kugurisha02@nahanutri.com