I-Peptide yeCosmetic ethengiswa kakhulu i-Nonapeptide-1 CAS 158563-45-2
Ingcaciso yeMveliso
- Kwimarike yehlabathi yokulungisa ukufiphala, amabala amnyama, kunye nebala lolusu elingalinganiyo, abathengi banamhlanje bayayeka ukusebenzisa izinto ezikhanyisayo zemveli ezirhabaxa nezicaphukisayo. Endaweni yoko, bafuna izinto ezininzi. echanekileyo, ethambileyo, kwaye esebenza kakhulu iiteknoloji zebhayoloji ezijoliswe kuzo. I-Nonapeptide-1 yinkampani eyaziwayo kwihlabathi liphela i-α-MSH (i-alpha-melanocyte-stimulating hormone) i-biomimetic antagonist peptideNgoku "nqumla" imiqondiso yokulungisa i-melanin ekuqaleni, iye yaba sisithako esisebenzayo seenkwenkwezi esibalulekileyo sokwenza mhlophe, ukufiphala kwamabala, kunye nokunyusa ukukhanya.
- Isamkeli Esijoliswe Kuso: I-MC1 Receptor (i-Melanocortin-1 Receptor) kwiimembrane ze-melanocyte
- Indawo yeMarike ePhambili: I-arhente yokuthintela isignali ephuma phezulu, isikhanyisi esikhuselekileyo esikhumbeni, isilungisi sesikhumba esilwa nokudinwa/esilwa nokufiphala.
Uhlalutyo oluSisiseko
| Into yoHlalutyo | Inkcazo | Iziphumo |
| Inkangeleko | Umhlophe okanye umhlophe njengomgubo | Abafanelekileyo |
| Ukunyibilika | ≥100mg/ml(H2I) | Abafanelekileyo |
| Ukufuma | ≤ 8.0% | 3.2% |
| I-acetic acid | ≤ 15.0% | 11.5% |
| Ubunyulu | ≥ 98.0% | 98.3% |
Indlela Yesayensi
Izinto zokwenza mhlophe zemveli (ezifana ne-arbutin okanye i-kojic acid) zisebenza kakhulu phakathi ukuya ezantsi ngokuthintela umsebenzi we-tyrosinase emva iseli sele ivuselelwe. I-Nonapeptide-1 ithatha inyathelo eliya phambili ngokusebenza njengekhaka lokuzikhusela kwi- ngokupheleleyo ukuveliswa kwe-melanin:
- Ukhuphiswano lokuzibophelela kwi-MC1R
Xa ulusu luvezwa kwimitha ye-UV okanye izinto ezibangela ukudumba, iiseli ze-basal zikhupha i-α-MSH. Le hormone isebenza njenge "key" efaka kwi-MC1 Receptor ("lock") kumphezulu we-melanocyte, nto leyo ebangela ukuveliswa kwe-tyrosinase kunye ne-melanin.
- Ukuphazamiseka kweSignali
I-Nonapeptide-1 isebenza njenge-biomimetic "decoy key" egqibeleleyo. Iqala ngokubophelela kwi-MC1 receptor, iyivale kwaye ithintele i-α-MSH yokwenyani ekunamatheleni.
- Isiphumo seZero-Isiphumo
Ukuba ayifumaneki imiyalelo ye-catalytic evela kwi-α-MSH, i-melanocyte ihlala ikwimeko yokuphumla. Oku kuthintela ngempumelelo ukuveliswa ngokugqithisileyo kunye nokuqokelelwa kwe-melanin kumthombo wayo.
Iingenelo kunye neeNzuzo zobugcisa
Ukudibanisa iNonapeptide-1 yethu kwimigca yemveliso yakho kubonelela ngeenzuzo ezininzi ezicacileyo zokukhuphisana:
- Ukuphela kweNdawo ekujoliswe kuyo kunye noBusuku beTone
Uvavanyo lweklinikhi lubonisa ukuba ukusetyenziswa rhoqo kweNonapeptide-1 kunciphisa kakhulu umbala obangelwa yi-UV, ukunyamalala kwe-chloasma ngokucwangcisiweyo, amabala elanga, kunye namabala emva kwe-acne ngelixa kubonakalisa umbala okhanyayo.
- Ilungele ulusu olubuthathaka oluyi-100%
Ngokungafaniyo neNiacinamide enamandla aphezulu (efuna ukuqina kolusu) okanye ii-AHA (ezithwala iingozi zokuxobuka kwamakhemikhali), iNonapeptide-1 ihambelana kakhulu ne-bio. Ayibangeli bomvu, ukuxobuka, okanye ukurhawuzelela, nto leyo eyenza ukuba ibe lolona khetho luphambili kwi- imigca ekhanyayo yolusu ebuthathaka.
- Isiqinisekiso soBumsulwa obuPhezulu kakhulu (≥ 98%)
Siveliswe ngetekhnoloji ephucukileyo, sisusa ngokungqongqo iintsalela zempendulo kunye nee-amino acid zasimahla, siqinisekisa ukhuseleko oluphezulu lwezinto ezikrwada.
Isicelo
Indalo ethambileyo kunye nokuchaneka okuphezulu kokujolisa kweNonapeptide-1 kuyenza ibe nokuguquguquka kwiindlela ezahlukeneyo zokhathalelo lolusu:
- IiSerums ezichasene nebala kunye nezokulungisa ezijolise kuzo
Ingasebenza njengesithako esibalulekileyo okanye idityaniswe nezinto ezizinzileyo zeVitamin C ukwenza unyango lokukhanyisa oluneendlela ezininzi, olukumgangatho ophezulu.
- Iikrimu zelanga ezisebenza kakuhle kunye neekhrimu zasemini
Ukongeza iNonapeptide-1 kwiimveliso zokhathalelo lwelanga kudala iluphu yokukhusela "ngaphandle-ukuzikhusela, ngaphakathi-kwebhloko", nto leyo ephucula kakhulu ukusebenza kwemveliso mhlophe kunye nempendulo yabasebenzisi.
- Iimaski zoBuyiselo emva kwenkqubo kunye nezoBuyiselo
Ilungele ukuzola ii-melanocytes ngexesha le-hyperpigmentation-probe I-PIH (i-Post-Inflammatory Hyperpigmentation) isigaba esilandelayo emva kweenkqubo zonyango (ezifana nokukrazula iikhemikhali okanye i-fractional lasers).
