Cosmetic Peptide Copper Tripeptide-1/Copper Peptide Powder GHK-CU
Product Description
- GHK-Cu is a naturally occurring tripeptide composed of three amino acids (glycine, histidine, lysine) chelated with copper ions. GHK-Cu not only is a cosmetic active ingredient but a research hotspot in regenerative medicine. It is typically labeled as "Copper Tripeptide-1" or "Blue Copper Peptide" in skincare ingredient lists, becoming a core ingredient for high-end skincare brands with its signature blue appearance and exceptional repair efficacy.
- After penetrating into the skin, blue copper peptide can induce fibroblasts to form collagen by releasing signals. Copper ions attached to blue copper peptides can enter the cell and release after encountering enzymes. Copper ions themselves are important components for many enzymatic reactions. Proteoglycan is an important component of extracellular matrix, and copper blue peptide can promote the formation of skin to make skin full and elastic.
Basic Analysis
| Items | Specifications | Results |
| Appearance | Blue crystalline powder | Complies |
| Identity by ESI-MS | MW:401.91 | Complies |
| Purity (HPLC) | ≥98.0% | 99.92% |
| Peptide Content (By N) | ≥80% | 81.51% |
| Copper content | 8.0-16% | 11.89% |
| Water (K.F.) | ≤8.0% | 5.18% |
| Chloride Content (IC) | ≤10.0% | Complies（7.05%） |
| PH (0.2%Water Soln.) | 5.5-7.5 | 6.20 |
| Solubility | ≥100mg/ml(H2O) | Complies |
| Lead (mg/kg) | ≤10 | < 10 |
| Arsenic (mg/kg) | ≤2 | < 2 |
| Mercury (mg/kg) | ≤1 | < 1 |
| Cadmium (mg/kg) | ≤5 | < 5 |
| Total plate count (cfu/g) | ≤1000 | Complies |
| Yeast & mould (cfu/g) | ≤100 | Complies |
| Conclusion | Conforms to standard | |
Function
- Tighten and relax skin, improve elasticity.
- Improve skin density and compactness.
- Reduce fine lines and deep wrinkles.
- Improve skin transparency.
- Reduce light damage and mottled pigmentation.
- Strongly increase the proliferation of keratinocytes.
- Enhance Collagen Remodeling and Anti-aging
- Improve Wound Healing and Tissue Regeneration
- Antioxidant and Anti-inflammatory
- Enhance Hair Regeneration and Scalp Health
Application
- High-end Skincare (Core Market)
GHK-Cu is a star ingredient in anti-aging skincare:
✅ Serums and Ampoules: High-concentration intensive repair
✅ Face Creams and Eye Creams: Daily anti-aging care
✅ Mask Products: Emergency repair and intensive nourishment
✅ Post-procedure Repair Products: Recovery care after laser, microneedling, and chemical peels
✅ Supported Efficacy Claims: Skin firming, wrinkle reduction, elasticity improvement, barrier repair, and brightening.
- Medical Aesthetics and Post-operative Care
✅ Minimally Invasive Post-procedure Repair: Rapid recovery after microneedling, hydro-lifting, and thread lifting
✅ Laser Treatment Support: Skin reconstruction after fractional laser and picosecond laser
✅ Surgical Scar Management: Reducing postoperative scar formation and improving old scars
✅ Chronic Wound Care: Adjunctive treatment for diabetic foot ulcers and pressure sores
- Hair and Scalp Care
✅ Anti-hair Loss Serums: Scalp essences targeting androgenetic alopecia
✅ Hair Growth Products: Hair tonics promoting follicle health
✅ Scalp Care: Improving scalp microenvironment and reducing inflammation
- Pharmaceuticals and Regenerative Medicine (Frontier Field)
✅ Tissue Engineering: Functional modification of skin substitutes
✅ Wound Dressings: Advanced wound care products containing GHK-Cu
✅ Systemic Applications: Research on injectables in anti-aging medicine and chronic disease management
Synergy with Other Ingredients
The unique aspect of GHK-Cu lies in its "carrier peptide" identity, which can form synergies with other active ingredients:
| Paired Ingredient | Synergistic Effect | Usage Recommendation |
| Hyaluronic Acid | Dual enhancement of hydration + repair | Can be used simultaneously |
| Niacinamide | Enhanced anti-inflammatory + barrier repair | Morning and evening pairing |
| Vitamin C | Antioxidant synergy | Use at different times (VC morning, GHK-Cu evening) |
| Retinol | Complementary anti-aging | Alternate use, avoid simultaneous application |
| Growth Factors | Accelerated repair | Combined use during post-operative recovery |
Avoid simultaneous use with strong acids (such as high-concentration AHA, salicylic acid) or chelating agents to prevent affecting copper ion stability.
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