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What is Quercetin source?
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What is Quercetin source?

2024-12-17

What is Quercetin source?

Sophora Japonica Extract (Quercetin) is a powdered botanical extract with antioxidant and anti-inflammatory benefits. It may help with gut health/digestion, cardiovascular health, and immunity support. It may also provide anti-fatigue benefits. Applications include energy, endurance, recovery, and weight management for sports nutrition. The active compounds for this product are Quercetin Anhydrous / Quercetin Dihydrate.

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Health benefits of quercetin

Research has linked quercetin’s antioxidant properties to various potential health benefits.

Here are some of its top science-based benefits.

 

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  • May reduce inflammation

Free radicals may do more than simply damage your cells. High levels of free radicals may help activate genes that promote inflammation. Thus, high levels of free radicals may lead to an increased inflammatory response.

While a little inflammation is necessary to help your body heal and fight infections, persistent inflammation is linked to health problems, including certain cancers, as well as heart and kidney diseases.

Studies show that quercetin may help reduce inflammation.

In test-tube studiesTrusted Source, quercetin reduced markers of inflammation in human cells, including the molecules tumor necrosis factor alpha (TNFα) and interleukin-6 (IL-6).

An 8-week studyTrusted Source in 50 women with rheumatoid arthritis observed that participants who took 500 mg of quercetin experienced significantly reduced early morning stiffness, morning pain, and after-activity pain.

They also had reduced markers of inflammation, such as TNFα, compared to those who received a placebo.

While these findings are promising, more human research is needed to understand the compound’s potential anti-inflammatory properties.

  • May ease allergy symptoms 

Quercetin’s potential anti-inflammatory properties may provide allergy symptom relief.

Test-tube and animal studies found that it may block enzymes involved in inflammation and suppress inflammation-promoting chemicals, such as histamine.

For example, one studyTrusted Source showed that taking quercetin supplements suppressed peanut-related anaphylactic reactions in mice.

Still, it’s unclear whether the compound has the same effect on allergies in humans, so more research is needed before it can be recommended as an alternative treatment.

  • May have anticancer effects

Because quercetin has antioxidant properties, it may have cancer-fighting properties.

In a review of test-tube and animal studies, quercetin was found to suppress cell growth and induce cell death in prostate cancer cells.

Other test-tube and animal studies observed that the compound had similar effects in liver, lung, breast, bladder, blood, colon, ovarian, lymphoid, and adrenal cancer cells.

Though these findings are promising, human studies are needed before quercetin can be recommended as an alternative treatment for cancer.

  • May lower your risk of chronic brain disorders

Research suggestsTrusted Source that quercetin’s antioxidant properties may help protect against degenerative brain disorders, such as Alzheimer’s disease and dementia.

In one studyTrusted Source, mice with Alzheimer’s disease received quercetin injections every 2 days for 3 months.

By the end of the study, the injections had reversed several markers of Alzheimer’s, and the mice performed much better on learning tests.

In another studyTrusted Source, a quercetin-rich diet reduced markers of Alzheimer’s disease and improved brain function in mice at the early middle stage of the condition.

However, the diet had little to no effect on animals with middle-late stage Alzheimer’s.

Coffee is a popular beverage that has been linked to a lower risk of Alzheimer’s disease.

In fact, research showsTrusted Source that quercetin, not caffeine, is the primary compound in coffee that’s responsible for its potential protective effects against this illness.

Though these findings are promising, more research in humans is needed.

  • May reduce blood pressure

High blood pressure affects 1 in 3 American adults. It raises your risk of heart disease — the leading cause of death in the United States.

Research suggestsTrusted Source that quercetin may help reduce blood pressure levels. In test-tube studiesTrusted Source, the compound appeared to have a relaxing effect on blood vessels.

When mice with high blood pressure were given quercetin daily for 5 weeks, their systolic and diastolic blood pressure values (the upper and lower numbers) decreased by an average of 18% and 23%Trusted Source, respectively.

Similarly, a reviewTrusted Source of 9 human studies in 580 people found that taking more than 500 mg of quercetin in supplement form daily reduced systolic and diastolic blood pressure by an average of 5.8 mm Hg and 2.6 mm Hg, respectively.

Although these findings are promising, more human studies are needed to determine whether the compound could be an alternative therapy for high blood pressure levels.

Other potential benefits

Here are several other potential benefits of quercetin:

  • May help combat aging. Test-tube and animal research suggestsTrusted Sourcethat quercetin may help rejuvenate or eliminate aging cells and reduce markers of aging. However, more human research is needed.
  • May aid exercise performance.A reviewTrusted Source of 11 human studies found that taking quercetin may slightly improve endurance exercise performance.
  • May aid blood sugar control.Human and animal researchTrusted Source indicates that the compound may reduce fasting blood sugar levels and protect against complications of diabetes.

Forms of Quercetin Supplements

Quercetin supplements come in pill or capsule form and are often combined with bromelain, an anti-inflammatory enzyme from pineapple. Water-soluble forms of quercetin, such as hesperidin-methyl-chalcone (HMC) or quercetin-chalcone, are also available.

 

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Dosage

People can get quercetin through their diet by eating a range of fruit and vegetables daily.

Onions are amongst the richest sources of dietary flavonoids you can eat, providing 28.4–48.6 milligrams (mg)Trusted Source of quercetin per 100 g

Quercetin is available as a nutritional supplement, typically in doses of 500 to 1000 mgTrusted Source daily.

Supplements may also include other substances, such as bromelain or vitamin C, which may help the body absorb quercetin more effectively.