Sayansi Kumbuyo kwa Turmeric Root Extract's Anti-Cancer Properties

Turmeric ndi chomera chomwe chakhala chikugwiritsidwa ntchito kwazaka zambiri muzamankhwala azikhalidwe chifukwa cha zabwino zake zambiri zaumoyo. Chimodzi mwazinthu zazikulu zomwe zimapezeka mu turmeric ndi curcumin, yomwe yawonetsedwa kuti ili ndi antioxidant komanso anti-inflammatory properties. Komabe, kafukufuku waposachedwapa wapezanso kuthekera kwa mizu ya turmeric polimbana ndi khansa.

Aogubio ndi kampani yapadera yomwe imapanga ndikugawa zinthu zomwe zimagwira ntchito pamankhwala, zopangira, ndi zopangira mbewu. Monga gawo lazogulitsa zawo, amapereka mizu ya turmeric, yomwe yatsimikiziridwa mwasayansi kuti ili ndi zotsutsana ndi khansa.

Khansara ndi matenda oopsa omwe amakhudza anthu mamiliyoni ambiri padziko lonse lapansi. Zimadziwika ndi kukula kosalamulirika ndi kugawanika kwa maselo osadziwika bwino m'thupi. Thandizo lachikale la khansa, monga chemotherapy ndi radiation therapy, nthawi zambiri zimakhala ndi zotsatirapo zoipa ndipo nthawi zina zimakhala zosathandiza. Choncho, pali kufufuza kosalekeza kwa mankhwala achilengedwe omwe amatha kuthana ndi khansara ndi zotsatira zochepa.

Kafukufuku wambiri tsopano walumikiza mizu ya turmeric ku anti-cancer properties. Kafukufuku wofalitsidwa mu nyuzipepala ya "Cancer Research and Treatment" wasonyeza kuti curcumin, chigawo chogwira ntchito mu turmeric, chimalepheretsa kukula kwa maselo a khansa. Makamaka, kuchotsa muzu wa turmeric kwawonetsedwa kuti kuletsa kukula kwa maselo a khansa ya ovarian mu hamsters achi China pamagulu a 0.4mg/ml. Imawonetsanso zotsatira za cytotoxic pa ma lymphocyte ndi ma cell a Dalton's lymphoma, kuwonetsa kuthekera kwake ngati chithandizo chamitundu yosiyanasiyana ya khansa.

Zotsatira zotsutsana ndi khansa za turmeric root extract zimakhulupirira kuti zimakhala chifukwa cha zomwe zimagwira ntchito, curcumin. Curcumin yapezeka kuti imaletsa njira zingapo zowonetsera zomwe zimakhudzidwa ndi kukula kwa maselo a khansa ndi kupulumuka. Itha kupondereza kuyambitsa kwa nuclear factor-kappa B (NF-kB), protein complex yomwe imayang'anira kutupa komanso imathandizira kwambiri pakukula kwa khansa. Poletsa NF-kB, curcumin imatha kuletsa kufotokoza kwa majini omwe akukhudzidwa ndi kukula kwa chotupa.

Kuphatikiza apo, curcumin yapezeka kuti imapangitsa kuti apoptosis, kapena kufa kwa cell kufa, m'maselo a khansa. Apoptosis ndi njira yachilengedwe yomwe imachotsa ma cell achilendo kapena owonongeka m'thupi. Maselo a khansa ali ndi mphamvu yochepa ya apoptosis, yomwe imathandizira kukula kwawo kosalamulirika. Curcumin imatha kubwezeretsanso kuthekera kwa ma cell a khansa kuti akumane ndi apoptosis, ndikulepheretsa kuchuluka kwawo.

Njira ina yomwe curcumin imakhala ndi zotsatira zotsutsana ndi khansa ndi kupyolera mu kusintha kwa epigenetic. Epigenetics imatanthawuza kusintha kwa mafotokozedwe a majini omwe samaphatikizapo kusintha kwa DNA. Zimagwira ntchito yofunika kwambiri pakukula kwa khansa komanso kukula. Curcumin yasonyezedwa kuti imakhudza maonekedwe a majini osiyanasiyana omwe amakhudzidwa ndi chotupa chotupa ndi oncogenesis kupyolera mu kusintha kwa epigenetic, monga DNA methylation ndi histone acetylation.

Ngakhale zomwe zapezedwa zokhudzana ndi zotsutsana ndi khansa za turmeric root extract, kufufuza kwina kumafunikabe kuti timvetse bwino njira zake zogwirira ntchito ndi zomwe zingagwiritsidwe ntchito pochiza khansa. Mayesero azachipatala ali mkati kuti awone mphamvu ndi chitetezo cha curcumin ngati chithandizo chothandizira mitundu yosiyanasiyana ya khansa.

Pomaliza, kuchotsa mizu ya turmeric, makamaka chigawo chake chogwira ntchito cha curcumin, chawonetsa zotsutsana ndi khansa. Aogubio, kampani yapadera yopanga ndi kugawa zinthu zomwe zimagwira ntchito pamankhwala, imapereka mizu ya turmeric ngati njira ina yachilengedwe polimbana ndi khansa. Ndi kuthekera kwake kuletsa kukula kwa maselo a khansa, kuyambitsa apoptosis, ndikusintha njira za epigenetic, turmeric root extract ili ndi kuthekera kwakukulu ngati chithandizo chothandizira chithandizo cha khansa. Komabe, kufufuza kwina ndi maphunziro azachipatala ndikofunikira kuti mufufuze mokwanira zomwe zingatheke ndikuwonetsetsa kuti zimagwira ntchito komanso chitetezo chake.