N'ihe gbasara ahụike na ahụike, ịchọta ihe mgbakwunye kwesịrị ekwesị nwere ike ime ka ụwa dị iche. Keira na-aga ịgwa gị maka resveratrol na post a taa. Resveratrol bụ onye ama ama n'ụwa n'ihi Paradox French nke a tụlere na 1990, mgbe e kwenyere na ihe kpatara ndị France na-eri nri nwere nnukwu abụba anaghị ebute ọrịa obi bụ n'ihi na resveratrol dị na mmanya na-acha ọbara ọbara nke ha na-aṅụkarị. .
Kemgbe ahụ, a ka na-achọpụta resveratrol maka uru ahụike ya, gụnyere antioxidant, mgbochi mkpali, anticancer, na mmetụta nchebe obi.
Kedu ihe bụ resveratrol?
Resveratrol, ihe na-abụghị flavonoid polyphenol organic compound, bụ antitoxin nke ọtụtụ osisi na-emepụta mgbe a na-akpali ya, na usoro kemịkal C14H12O3. Na 1940, onye ọkà mmụta Japan bụ MichioTakaoka nke mbụ kewapụrụ resveratrol na Veratrum album na ezinụlọ lily, ma mesịa nweta ya na Polygonum cuspidatum na ezinụlọ polygonum na 1963. Enwere ike ịmepụta ya na akwụkwọ vine na akpụkpọ mkpụrụ vaịn ma bụrụ ihe na-eme ihe na-edozi ahụ na mmanya na mmanya. ihe ọṅụṅụ mkpụrụ vaịn. A na-etinye ya ngwa ngwa site n'ọnụ wee pụta na mmamịrị na stool mgbe metabolism gasịrị. Nnwale in vitro na anụmanụ egosila na resveratrol nwere antioxidant, mgbochi mkpali, mgbochi cancer na mmetụta nchebe obi.
Resveratrolna-ekesa n'ọtụtụ ebe na osisi, na dị ka nke 2021, a chọtara ya na ihe karịrị osisi 70 sitere na ezinụlọ 21, karịsịa, itis dị na Vitis, Ampelopsis, Polygonum, Arachis, Cassia, Sophora, Veratrum, Veratrum na Eucalyptus. Osisi a na-ahụkarị nke nwere resveratrol na-agụnye mkpụrụ vaịn, knotweed, peanuts, cassia, wdg. Usoro nhazi nke kemịkalụ nke resveratrol na usoro dị mfe na nke tozuru okè, a na-eji ngwaahịa dị elu na ọnụ ahịa mmepụta ihe dị ala maka nkwadebe maka mmepụta ihe, nke mere na ịnweta resveratrol abụghị ihe ọ bụla. ogologo dabere na mmịpụta na nkewa site na osisi. Usoro njikọ nke resveratrol na-eji mmeghachi omume Wittig eme ihe iji ghọta splicing nke mgbanaka benzene abụọ, na mkpụrụ nwere ike iru karịa 50%.
Gịnị bụ mmetụta nke resveratrol?
- Mgbochi ịka nká
N'ime afọ ndị na-adịbeghị anya, a chọpụtala na ọtụtụ polyphenols nwere mmetụta mgbochi-oxidation na mgbochi na-enweghị isi.
Dị ka antioxidant eke, resveratrol nwere mkpochapụ onwe ya siri ike na mgbochi lipid peroxidation, na ọbụna ma e jiri ya tụnyere omenala antioxidants dị ka vitamin C, butylhydroxytoluene, tocopherol, resveratrol nwere mmetụta antioxidant ka mma.
Resveratrolna-egosipụta mmetụta antioxidant ya tumadi site na nchacha ma ọ bụ igbochi radicals efu, na-egbochi peroxidation lipid, na-achịkwa ọrụ nke enzymes metụtara antioxidation na usoro ndị ọzọ.
Resveratrol na-eguzogide ịka nká nke peroxidation lipid kpatara site na radicals free na metabolites ha. N'otu oge ahụ, resveratrol na-ewepu free radicals, na-ebelata ọdịnaya nke H₂O₂ na akpụkpọ ahụ, na-eme ka ọrụ ATPase dịkwuo mma, ma si otú ahụ na-enwe mmetụta nke igbu oge ịka nká.
- Jikwaa shuga ọbara
Ọrịa shuga bụ ọrịa na-adịghị ala ala nke na-ahụkarị, mana ọ bụkwa nke a na-egbochi ya ngwa ngwa, mana n'ihi nke a na-emekarị ka ndị mmadụ were ya gwurie egwu, nsogbu nke ọrịa shuga, bụ arteriosclerosis, na mgbakwunye na-abawanye ohere nke myocardial infarction, ọrịa strok, ma ọ bụrụ na ọ dị mkpa. na-emetụta microvessels akụrụ, ga-eme ka ọdịda akụrụ pụtakwuo, yabụ otu esi achịkwa shuga dị n'ọbara dị mkpa maka ndụ.
N'ime obere ọmụmụ, resveratrol (150 mg kwa ụbọchị maka ụbọchị 30, DSM proprietary components resVida) kwalitere ọkwa shuga dị n'ọbara (site na 4.2%) na ọkwa insulin (site na 13.7%) na ndị buru ibu.
- Mgbochi tumor, mgbochi ọrịa kansa
Resveratrol nwere mmetụta inhibitory dị ịrịba ama na hepatocellular carcinoma, ọrịa ara ara, cancer colon, ọrịa kansa afọ, leukemia na mkpụrụ ndụ tumo ndị ọzọ. Ụfọdụ ndị ọkà mmụta ekwenyela na resveratrol nwere mmetụta mgbochi doro anya na sel melanoma site na usoro MTT na cytometry eruba.
A kọwo na resveratrol nwere ike ịkwalite ọgwụgwọ radieshon cancer, mee mmetụta "1 + 1> 2", ma gbochie ọrụ nke mkpụrụ ndụ sel kansa nke ọma. Ma ka ọ dị ugbu a, n'ihi mgbagwoju anya nke usoro mgbochi tumor nke resveratrol, ndị nchọpụta enwebeghị nkwenye na usoro ya.
- Ọrụ ndị ọzọ
Resveratrol nwekwara antibacterial, antioxidant, immunomodulatory, antiasthmatic na ihe omume ndụ ndị ọzọ. A na-achọ resveratrol nke ukwuu n'ihi ọrụ ya dị iche iche.
Kedu ka esi ewepụ resveratrol?
- Usoro mmịpụta ihe ọkụkụ
A na-ewepụta Resveratrol ma sachaa ya site na mkpụrụ vaịn, knotweed na ahụekere. The crude mmịpụta technology tumadi na-agụnye organic ihe mgbaze mmịpụta usoro, alkali mmịpụta usoro na enzyme mmịpụta usoro, ngwa ndakwa nri aka mmịpụta usoro, CO2 supercritical mmịpụta, ultrasonic enyemaka mmịpụta na ndị ọzọ ụzọ ọhụrụ na-etinyere. Ebumnuche bụ isi nke ịdị ọcha bụ ikewapụ resveratrol cis, trans isomer na resveratrol Xib site na resveratrol raw ewepụtara iji nweta trans-resveratrol. Ụzọ nchacha a na-ejikarị eme ihe bụ chromatography, silica gel kọlụm chromatography, chromatography nke obere oyi akwa, chromatography mmiri mmiri dị elu na ihe ndị ọzọ.
- Usoro synthesis
N'ihi obere ọdịnaya nke resveratrol na osisi na ọnụ ahịa mmịpụta dị elu, iji kemịkalụ, usoro ndu na mkpụrụ ndụ ihe nketa iji nweta resveratrol aghọwo ụzọ dị mkpa na usoro mmepe. Mmeghachi omume Perkin, mmeghachi omume Hech na mmeghachi omume Witting-Hormer bụ ụzọ kemịkalụ tozuru oke maka njikọ nke resveratrol, yana mkpụrụ nke 55.2%, 70% na 35.7%, n'otu n'otu. Iji teknụzụ injinia mkpụrụ ndụ ihe nketa iji chịkwaa ma ọ bụ melite ụzọ biosynthesis nke resveratrol iji nweta ahịrị osisi na-amịpụta dị elu; Mmụba nke resveratrol mụbara site na 1.5 ~ 3.0 ugboro site na mutagenesis na ụzọ ndị ọzọ.
Aogubio bụ ụlọ ọrụ ọkachamara na mmepụta na nkesa nke ọgwụ na-arụ ọrụ ọgwụ, akụrụngwa na ihe ọkụkụ, gụnyere nutraceuticals maka mmepụta ihe mgbakwunye mmadụ. Anyị na-elekwasị anya na ọgwụ na ngwaahịa maka ọgwụ, nri, nutraceutical na ịchọ mma ụlọ ọrụ, ma na-agba mbọ na-enye ndị ahịa ihe dị elu mma na irè mgbakwụnye.Resveratrol bụ otu n'ime ihe ndị anyị na-enye na ihe ọkụkụ.
NTỤKWASỊ OBI ỊDỊ MMA:
Ụlọ ọrụ anyị nwere ụlọ nyocha na-eji chromatography gas ọgbara ọhụrụ iji nwalee ịdị ọcha na ike nke akụrụngwa anyị; n'ịhụ na ndị ahịa anyị na-enweta ngwaahịa kacha mma mgbe niile.
NDỊ ỌRỤ NLEKỌTA NDỊ AHỊA:
N'ịkwado ihe mgbaru ọsọ anyị nke imezu amụma nkwenye afọ ojuju, ndị otu anyị raara onwe ha nye dị njikere mgbe niile inye ndị ahịa anyị ụlọ ọrụ na-eduga ọrụ ndị ahịa n'akụkụ ọ bụla nke usoro ahụ.
Ọ bụrụ na ịchọrọ ịmata maka ma ọ bụ zụta ezigbo resveratrol, biko kpọtụrụ Kayla.
Kpọtụrụ: Keira Zhang
Email: sales06@aogubio.com
Tel: +86 18066856327
Oge nzipu: Jan-08-2024
