Maualuga Maualuga Nicotinamide Adenine Dinucleotide Nad Cas 53-84-9
O le a le NAD+?
NAD e puupuu mo le nicotinamide adenine dinucleotide.
O se coenzyme ma o loʻo i ai ile NAD + form ma le NADH form.
O iinei tatou te talanoa e uiga i le NAD +.
Lenei, o lo'o i ai se tamai fale eletise i totonu o sela uma o lou tino. E ta'ua o le mitochondria.
Mitochondria o le puna o le malosi uma i le tino. Mai le siiina o le mamafa, emo, eliina meaai i le tata o le fatu, o mea uma e faalagolago i le mitochondria.
NAD + o le puna muamua lea e tausia ai le mitochondria gaioiga.
A o matou laiti, sa tumu o matou tino i le NAD +. Matou te maua uma le NAD + matou te manaʻo ai.
Ae a o tatou matutua, ua amata ona paʻu le maualuga ole NAD + pei o maʻa. I le 20 tausaga uma, e pa'ū lau NAD + i le 50%.
SU'EGA FA'AVAE
| Su'ega Mea | Fa'amatalaga | I'uga |
| Fa'aaliga | Pa'epa'e i le samasama pauta po'o le pauta tioata | Fa'atatau |
| Fa'ailoaga | Fa'atasi ma le NMR | Fa'atatau |
| Na i totonu (ICP-OES) | ≤0.5% | 0.01% |
| Vai | ≤10.0% | 4.7% |
| PH | 2.0-4.0 | 3.3 |
| Mama (HPLC) | ≥98.5% | 99.71% |
| Su'ega | ≥97.0% | 99.28% |
| Uamea mamafa | ||
| Ta'ita'i(Pb) | ≤0.5ppm | Fa'atatau |
| Arsenic(As) | ≤0.5ppm | Fa'atatau |
| Cadmium(Cd) | ≤0.5ppm | Fa'atatau |
| Mercury(Hg) | ≤0.5ppm | Fa'atatau |
| Su'esu'ega ole Spectroscopy | ||
| A340/A260 | 0.39-0.47 (0.43±0.04) | 0.42 |
| A250/A260 | 0.75-0.91 (0.83±0.08) | 0.83 |
| A280/A260 | 0. 19-0.23 (0.21±0.02) | 0.22 |
| ε260 (pH=7.5) | 16.2- 19.8(103L·mol- 1·cm- 1)( 18 .0± 1.8) ×103 | 17.9×103 |
| ε340 (pH=10) | 5.7-6.9(103L·mol- 1·cm- 1)(6.3±0.6) ×103 | 6.5×103 |
| Solvent totoe | ||
| Methanol | ≤ 1.0% | ND |
| Ethanol | ≤2.0% | 0.02% |
| Microbial | ||
| Numera o Kolone | ≤750CFU/g | |
| Escherichia Coli | ND | |
Galuega
Nicotinamide Adenine Dinucleotide (NAD) o se coenzyme taua e taʻalo ai se sao taua i le faʻaogaina o le malosi o le telefoni feaveaʻi ma le toe faʻafoʻiina. O nisi nei o faʻamatalaga faʻapolofesa ile NAD:
- Ole metabolism ole malosi ole cellular:O le NAD o se mea taua i le faʻaliliuina o meaʻai i meaʻai i le telefoni feaveaʻi. E auai i faiga e pei o le glycolysis, manava anaerobic, ma le manava aerobic i totonu o sela, fesoasoani e gaosia le mana'omia adenosine triphosphate (ATP) sapalai malosi.
- Aafiaga Antioxidant:O le NAD e iai foʻi se vaega taua o le antioxidant i sela. E mafai ona galue fa'atasi ma enzymes antioxidant e fa'amama ai fa'ama'i sa'oloto ma isi fa'ama'i fa'ama'i, fa'aitiitia le fa'aleagaina o sela, fesoasoani e fa'atumauina le soifua maloloina o le sela ma fa'atuai ai le faagasologa o le matua.
- DNA toe faaleleia:O loʻo aʻafia foʻi le NAD i le faʻagasologa o le toe faʻaleleia o DNA, fesoasoani e faʻasaʻo le faʻaleagaina o mole mole DNA ma faʻamaumau le faʻamaoni o faʻamatalaga faʻasologa o le sela.
- Fa'aleleia le fa'aogaina o le puipuiga:O le NAD e faʻamalosia le gaioiga ma le gaioiga o sela puipuia ma lagolagoina le tali atu a le tino i siama, siama ma isi faʻamaʻi.
- Faʻaleleia le soifua maloloina cardiovascular ma cerebrovascular:NAD ua faʻamaonia e faʻaleleia le soifua maloloina o le cardiovascular ma cerebrovascular. E fesoasoani i le faʻaleleia o le elasticity ma le gaioiga o puipui o le toto ma faʻaleleia le toto, faʻaitiitia ai le lamatiaga o faʻamaʻi cardiovascular ma cerebrovascular.
E le gata i lea, ua maua le NAD e fesoʻotaʻi ma le tele o isi faʻagasologa o le physiological ma faʻamaʻi, e pei o aʻafiaga o le kanesa, faʻamaʻi neurodegenerative, maʻi suka, atuatuvale, ma isi. .
