High Purity Nicotinamide Adenine Dinucleotide Nad Cas 53-84-9
Chii chinonzi NAD+?
NAD ipfupi ye nicotinamide adenine dinucleotide.
Iyo coenzyme uye iripo muNAD + fomu uye NADH fomu.
Pano tinotaura nezveNAD +.
Ikozvino, pane diki remagetsi chirimwa musero rega rega remuviri wako. Inonzi mitochondria.
Mitochondria ndiko kunobva simba rose mumuviri. Kubva pakusimudza masimbi, kubwaira, kugaya chikafu kusvika kurova kwemoyo, zvese zvinotsamira pamitochondria.
NAD+ ndiyo yekutanga sosi yekuchengeta mitochondria chiitiko.
Pataiva vadiki, miviri yedu yakanga yakazara neNAD+. Isu tinowana ese NAD + yatinoda.
Asi sezvatinokura, mazinga edu eNAD + anotanga kudonha sematombo. Makore makumi maviri ega ega, yako NAD+ level inodonha ne50%.
BASIC ANALYSIS
| Testing Items | Zvinotsanangurwa | Results |
| Chitarisiko | Hupfu hwakachena kusvika kuyero kana hupfu hwecrystalline | Conforms |
| Identification | Ita zvinoenderana neNMR | Conforms |
| Na Content (ICP-OES) | ≤0.5% | 0.01% |
| Mvura | ≤10.0% | 4.7% |
| PH | 2.0-4.0 | 3.3 |
| Kuchena (HPLC) | ≥98.5% | 99.71% |
| Assay | ≥97.0% | 99.28% |
| Heavy metal | ||
| Kutungamira (Pb) | ≤0.5ppm | Conforms |
| Arsenic (As) | ≤0.5ppm | Conforms |
| Cadmium(Cd) | ≤0.5ppm | Conforms |
| Mercury(Hg) | ≤0.5ppm | Conforms |
| Kuonekwa kweSpectroscopy | ||
| A340/A260 | 0.39-0.47 (0.43±0.04) | 0.42 |
| A250/A260 | 0.75-0.91 (0.83±0.08) | 0.83 |
| A280/A260 | 0. 19-0.23 (0.21±0.02) | 0.22 |
| ε260 (pH=7.5) | 16.2- 19.8(103L·mol- 1·cm- 1)( 18 .0± 1.8) ×103 | 17.9×103 |
| ε340 (pH=10) | 5.7-6.9(103L·mol- 1·cm- 1)(6.3±0.6) ×103 | 6.5 × 103 |
| Residual Solvent | ||
| Methanol | ≤ 1.0% | ND |
| Ethanol | ≤2.0% | 0.02% |
| Microbial | ||
| Colonies Number | ≤750CFU/g | |
| Escherichia Coli | ND | |
Function
Nicotinamide Adenine Dinucleotide (NAD) yakakosha coenzyme inoita basa rakakosha muserura simba metabolism uye redox maitiro. Heano mamwe ehunyanzvi sumo kuNAD:
- Serura simba metabolism:NAD chinhu chakakosha pakushandura chikafu chiri muchikafu kuita simba remagetsi. Inotora chikamu mumatanho akadai se glycolysis, anaerobic kufema, uye aerobic kufema mukati memasero, zvichibatsira kugadzira inodiwa adenosine triphosphate (ATP) simba rekupa.
- Antioxidant effect:NAD inoitawo basa rakakosha re antioxidant mumasero. Inogona kushanda neantioxidant enzymes kutsvaira mahara radicals uye zvimwe zvinokuvadza oxidants, kuderedza oxidative kukuvadzwa kumaseru, kubatsira kuchengetedza hutano hwesero uye kunonoka kuchembera.
- DNA kugadzirisa:NAD inobatanidzwawo mukugadzirisa kweDNA, kubatsira kugadzirisa kukuvadzwa mumamorekuru eDNA uye kuchengetedza kutendeseka kweruzivo rwemajini esero.
- Wedzera immune function:NAD inosimudzira kuita uye kushanda kwemasero edziviriro uye inotsigira mhinduro ye immune system kune mavhairasi, mabhakitiriya uye mamwe hutachiona.
- Kuvandudza hutano hwemoyo uye cerebrovascular:NAD yakaratidza kuvandudza hutano hwemoyo uye cerebrovascular. Inobatsira kuwedzera elasticity uye kushanda kwemadziro emidziyo yeropa uye inovandudza kutenderera kweropa, nekudaro ichidzikisa njodzi yemoyo uye cerebrovascular chirwere.
Mukuwedzera, NAD yakawanikwa iine chokuita nemamwe maitiro akawanda ehupenyu uye zvirwere, zvakadai se-anti-cancer effects, neurodegenerative zvirwere, chirwere cheshuga, kuora mwoyo, etc. Zvisinei, kushandisa NAD sekuwedzera kana kurapwa kwemishonga kunoda kutsvakurudza kwakawanda uye kusimbiswa kwekliniki. .
