High Purity Nicotinamide Adenine Dinucleotide Nad Cas 53-84-9
NAD + yog dab tsi?
NAD luv luv rau nicotinamide adenine dinucleotide.
Nws yog coenzyme thiab muaj nyob rau hauv NAD + daim ntawv thiab NADH daim ntawv.
Ntawm no peb tham txog NAD +.
Tam sim no, muaj lub zog me me hauv txhua lub cell ntawm koj lub cev. Nws yog hu ua mitochondria.
Mitochondria yog lub hauv paus ntawm txhua lub zog hauv lub cev. Los ntawm kev nqa qhov hnyav, ntsais muag, zom zaub mov kom lub plawv dhia, txhua yam tso siab rau mitochondria.
NAD + yog lub hauv paus tseem ceeb los khaws cov kev ua mitochondria.
Thaum peb tseem hluas, peb lub cev puv NAD+. Peb tau txais tag nrho NAD + peb xav tau.
Tab sis thaum peb muaj hnub nyoog, peb qib NAD + pib poob zoo li pob zeb. Txhua 20 xyoo, koj qib NAD + poob los ntawm 50%.
BASIC analysis
| Cov khoom kuaj | Specifications | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb mus rau yellowish hmoov los yog crystalline hmoov | Ua raws |
| Kev txheeb xyuas | Ua raws li NMR | Ua raws |
| Cov ntsiab lus (ICP-OES) | ≤ 0.5% | 0.01% |
| Dej | ≤ 10.0% | 4.7% |
| PH | 2.0-4.0 Nws | 3.3 |
| Purity (HPLC) | ≥98.5% | 99.71% |
| Assay | ≥97.0% | 99.28% |
| Hnyav hlau | ||
| Lead (Pb) | ≤0.5ppm | Ua raws |
| Arsenic (As) | ≤0.5ppm | Ua raws |
| Cadmium (Cd) | ≤0.5ppm | Ua raws |
| Mercury (Hg) | ≤0.5ppm | Ua raws |
| Spectroscopy Detection | ||
| A340/A260 | 0.39-0.47 (0.43 ± 0.04) | 0.42 ib |
| A250/A260 | 0.75-0.91 (0.83 ± 0.08 hli) | 0.83 ib |
| A280/A260 | 0.19-0.23 (0.21 ± 0.02) | 0.22 |
| ε260 (pH = 7.5) | 16.2-19.8 (103L· mol-1· cm-1)(18 .0 ± 1.8) × 103 | 17.9 × 103 |
| ε340 (pH = 10) | 5.7–6.9 (103L· mol-1· cm-1(6.3 ± 0.6) × 103 | 6.5 × 103 |
| Residual Solvent | ||
| Methanol | ≤ 1.0% | ND |
| Ethanol | ≤ 2.0% | 0.02% |
| Microbial | ||
| Colonies Number | ≤750CFU/g | |
| Escherichia Coli | ND | |
Muaj nuj nqi
Nicotinamide Adenine Dinucleotide (NAD) yog ib qho tseem ceeb coenzyme uas ua lub luag haujlwm tseem ceeb hauv cellular zog metabolism thiab redox cov tshuaj tiv thaiv. Nov yog qee qhov kev qhia ua haujlwm rau NAD:
- Cellular zog metabolism:NAD yog qhov tseem ceeb hauv kev hloov cov khoom noj hauv cov zaub mov rau hauv lub zog ntawm tes. Nws koom nrog cov txheej txheem xws li glycolysis, anaerobic respiration, thiab aerobic respiration nyob rau hauv cov hlwb, pab tsim cov adenosine triphosphate (ATP) lub zog uas yuav tsum tau.
- Antioxidant nyhuv:NAD tseem ua lub luag haujlwm tseem ceeb hauv cov hlwb. Nws tuaj yeem ua haujlwm nrog cov enzymes antioxidant kom tshem tawm cov dawb radicals thiab lwm yam teeb meem oxidants, txo oxidative puas hlwb, pab tswj kev noj qab haus huv ntawm tes thiab ncua kev laus.
- kho DNA:NAD tseem koom nrog hauv cov txheej txheem ntawm kev kho DNA, pab kho kev puas tsuaj hauv DNA molecules thiab tswj kev ncaj ncees ntawm cov xov tooj ntawm tes cov ntaub ntawv caj ces.
- Txhim khu kev tiv thaiv kab mob:NAD txhawb kev ua haujlwm thiab kev ua haujlwm ntawm lub cev tiv thaiv kab mob thiab txhawb lub cev tiv thaiv kab mob teb rau cov kab mob, kab mob thiab lwm yam kab mob.
- Txhim kho plawv thiab cerebrovascular noj qab haus huv:NAD tau raug pov thawj los txhim kho cov hlab plawv thiab cerebrovascular noj qab haus huv. Nws pab txhim kho elasticity thiab kev ua haujlwm ntawm cov hlab ntsha phab ntsa thiab txhim kho cov ntshav ncig, yog li txo qhov kev pheej hmoo ntawm cov kab mob plawv thiab cerebrovascular.
Tsis tas li ntawd, NAD tau pom tias muaj feem cuam tshuam nrog ntau lwm yam txheej txheem physiological thiab kab mob, xws li kev tiv thaiv mob qog noj ntshav, kab mob neurodegenerative, ntshav qab zib, kev nyuaj siab, thiab lwm yam. Txawm li cas los xij, siv NAD los ua tshuaj ntxiv lossis kev kho tshuaj yuav tsum muaj kev tshawb fawb ntxiv thiab kev soj ntsuam xyuas. .
