Babban Tsabta Nicotinamide Adenine Dinucleotide Nad Cas 53-84-9
Menene NAD+?
NAD gajere ne don nicotinamide adenine dinucleotide.
Yana da coenzyme kuma yana wanzu a cikin NAD+ da nau'in NADH.
Anan muna magana game da NAD +.
Yanzu, akwai ƙaramin tashar wutar lantarki a kowane tantanin halitta na jikin ku. Ana kiranta da mitochondria.
Mitochondria shine tushen dukkan kuzari a cikin jiki. Daga ɗaukar nauyi, kiftawa, narkewar abinci zuwa bugun zuciya, komai ya dogara da mitochondria.
NAD + shine tushen farko don kiyaye ayyukan mitochondria.
Lokacin da muke samari, jikinmu yana cike da NAD+. Muna samun duk NAD+ da muke so.
Amma yayin da muke tsufa, matakan NAD + sun fara faɗuwa kamar duwatsu. Kowace shekara 20, matakin NAD+ ɗin ku yana raguwa da 50%.
BASIC ANALYSIS
| Abubuwan Gwaji | Ƙayyadaddun bayanai | Sakamako |
| Bayyanar | Fari zuwa yellowish foda ko crystalline foda | Ya dace |
| Ganewa | Yi daidai da NMR | Ya dace |
| Abin ciki (ICP-OES) | ≤0.5% | 0.01% |
| Ruwa | ≤10.0% | 4.7% |
| PH | 2.0-4.0 | 3.3 |
| Tsaftace (HPLC) | ≥98.5% | 99.71% |
| Assay | ≥97.0% | 99.28% |
| Karfe mai nauyi | ||
| Jagora (Pb) | ≤0.5pm | Ya dace |
| Arsenic (AS) | ≤0.5pm | Ya dace |
| Cadmium (Cd) | ≤0.5pm | Ya dace |
| Mercury (Hg) | ≤0.5pm | Ya dace |
| Binciken Spectroscopy | ||
| A340/A260 | 0.39-0.47 (0.43± 0.04) | 0.42 |
| A250/A260 | 0.75-0.91 (0.83± 0.08) | 0.83 |
| A280/A260 | 0. 19-0.23 (0.21± 0.02) | 0.22 |
| ε260 (pH=7.5) | 16.2- 19.8 (103L·mol- 1· cm- 1) ( 18 .0± 1.8) ×103 | 17.9×103 |
| ε340 (pH = 10) | 5.7-6.9 (103L·mol- 1· cm- 1(6.3±0.6) ×103 | 6.5×103 |
| Residual Solvent | ||
| Methanol | ≤ 1.0% | ND |
| Ethanol | ≤2.0% | 0.02% |
| Microbial | ||
| Lambar Mallaka | ≤750CFU/g | |
| Escherichia Coli | ND | |
Aiki
Nicotinamide Adenine Dinucleotide (NAD) wani muhimmin coenzyme ne wanda ke taka muhimmiyar rawa a cikin metabolism na makamashin salula da halayen redox. Anan akwai wasu gabatarwar ƙwararru ga NAD:
- Salon makamashi metabolism:NAD shine mabuɗin mahimmanci don canza abubuwan gina jiki a cikin abinci zuwa makamashin salula. Yana shiga cikin matakai irin su glycolysis, numfashin anaerobic, da numfashi na aerobic a cikin sel, yana taimakawa wajen samar da makamashin adenosine triphosphate (ATP) da ake bukata.
- Tasirin Antioxidant:NAD kuma tana taka muhimmiyar rawa ta antioxidant a cikin sel. Zai iya yin aiki tare da enzymes antioxidant don kawar da radicals kyauta da sauran masu cutarwa masu cutarwa, rage lalacewar oxidative ga sel, taimakawa kula da lafiyar kwayar halitta da jinkirta tsarin tsufa.
- Gyaran DNA:Hakanan NAD yana shiga cikin tsarin gyaran DNA, yana taimakawa wajen gyara lalacewa a cikin kwayoyin halittar DNA da kiyaye amincin bayanan kwayoyin halitta.
- Haɓaka aikin rigakafi:NAD yana haɓaka aiki da aikin ƙwayoyin rigakafi kuma yana tallafawa martanin tsarin rigakafi ga ƙwayoyin cuta, ƙwayoyin cuta da sauran ƙwayoyin cuta.
- Inganta lafiyar zuciya da jijiyoyin jini:An tabbatar da NAD don inganta lafiyar zuciya da jijiyoyin jini. Yana taimakawa wajen haɓaka haɓakawa da aikin ganuwar jini da inganta yanayin jini, don haka rage haɗarin cututtukan zuciya da jijiyoyin jini.
Bugu da ƙari, an gano NAD yana da alaƙa da wasu matakai na ilimin lissafi da cututtuka, irin su maganin ciwon daji, cututtuka na neurodegenerative, ciwon sukari, damuwa, da dai sauransu. Duk da haka, yin amfani da NAD a matsayin kari ko magani na magunguna yana buƙatar ƙarin bincike da ingantaccen asibiti. .
