Kabka Nafaqada Heerka Cunnada Oleanolic Acid budada
Waa maxay oleanolic acid?
Oleanolic acid (OA), hydroxyl pentacyclic triterpenoid acid (HPTA) oo la mid ah betulinic acid, ursolic acid;
Halkee laga heli karaa oleanolic acid?
Qaar ka mid ah miraha sida tufaaxa, rummaanka, liin, bilberries, saytuun waxaa ku jira oleanolic acid.
| Magaca Dhirta | Maaddada Oleanolic acid | Habka tijaabada |
| Sirdoonkii dhalaalaya ayaa yidhi | 0.8028% | HPLC |
| Verbena Officinalis L | 0.071% -0.086% | HPLC |
| Prunella vulgaris L | 3.47% -4.46% | HPLC |
| Hemsley Chinensis Cogn. | 1.5% ilaa 2% | HPLC |
Hadda, geedo Chinese ahHemsley Chinensis Cognweli waa alaabta ceeriin ee ugu ganacsiga badan ee soo saarista oleanolic acid.
Hemsley Chinensis Cogn.Hordhac
Hemsleya chinensis Cogn.waa geed fuulitaan sanadle ah, sidoo kale waa dawo dhaqameed Shiinees ah.
- Qoyska: Cucurbitaceae
- Qabiilka: Gomphogyneae
- Genus: Hemsleya
- Noocyada: H. lovely
Dhirta waxaa lagu qaybiyaa gobollada Guangxi, Sichuan, Guizhou, Yunnan, Hubei, iwm. Waxay ku dhasheen cidhifka kaynta iyo geedaha dooxada ee joogga dhererkoodu yahay ilaa 2,000 mitir.
Maaddooyinka firfircoon: waxaa ku jira Hemslolide Mal, Ma3, H1; Chikusetsusaponin-Iva; dihydro cucurbitacin F-25-acetate; dilydrocucurbitacin F; oleanolic acid-beta-Hlucosyloleanolate; Hemsamabilinin A; Cu-curbitacinⅡb-2-beta-D-glucopyranoside.
Soo saarista Oleanolic acid ee Hemsleya Chinensis Cogn.
FALANQEYNTA AASAASIGA AH
| Shayga Falanqaynta | Tilmaamid | Natiijooyinka | Hababka Imtixaanka |
| Qiimayn | ≥98.0% | 98.4% | HPLC |
| Organoleptic | |||
| Muuqashada | Budada | U hoggaansamo | Organoleptic |
| Midabka | Budada crystalline off-caddaan | U hoggaansamo | Organoleptic |
| ur | Aan ur lahayn oo aan dhadhamin | U hoggaansamo | Organoleptic |
| Astaamaha Jirka | |||
| Luminta qalajinta | ≤0.5% | 0.01% | USP |
| Hadhaaga | ≤0.1% | 0.039% | USP |
| Wareegid gaar ah | 75.0°-83.0° | 78.2° | CP2010 |
| Biraha culus | |||
| Wadarta Biraha Culus | 20ppm ugu badnaan | U hoggaansamo | USPQaabka II |
| hogaanka (Pb) | 3pm NMT | U hoggaansamo | ICP-MS |
| Arsenic (As) | 2pm NMT | U hoggaansamo | ICP-MS |
| Cadmium (Cd) | 1pm NMT | U hoggaansamo | ICP-MS |
| Meerkuri (Hg) | 0.1pm NMT | U hoggaansamo | ICP-MS |
| Tijaabooyinka Microbiological | |||
| Wadarta tirada saxanada: | NMT 5,000 cfu/g | U hoggaansamo | AOAC |
| Khamiir & Caar: | NMT 300 cfu/g | U hoggaansamo | AOAC |
| Salmonella: | xun | U hoggaansamo | AOAC |
| E.Coli: | xun | U hoggaansamo | AOAC |
Shaqada
Oleanolic acid (ursolic acid) waa triterpenoid dabiici ah oo si weyn looga helo dhirta, sida bearberry, saytuun, blueberries, iwm.
- Ka-hortagga bararka iyo saamaynta antioxidant:Ursolic acid waxay leedahay waxqabadyo anti-bararka iyo anti-bararka oo muhiim ah. Waxay yareyn kartaa falcelinta bararka, waxay joojin kartaa sii deynta dhexdhexaadiyeyaasha caabuqa, waxay ka saartaa xagjirnimada xorta ah ee jirka, waxayna yareyn kartaa dhaawaca ay keento cadaadiska oksaydhka.
- Ilaalinta beerka:Ursolic acid waxay saameyn difaac ah ku leedahay beerka. Waxay kor u qaadaa dib u soo kabashada unugyada beerka iyo hagaajinta, yaraynta khatarta dhaawaca beerka. Ursolic acid waxay sidoo kale ka hortagi kartaa oo daweyn kartaa cudurrada beerka sida beerka dufanka leh iyadoo nidaamisa dheef-shiid kiimikaad ee beerka.
- Dhaqdhaqaaqa ka hortagga burooyinka:Ursolic acid waxay leedahay saameyn lid ku ah unugyada burooyinka qaarkood. Waxay samayn kartaa waxqabad ka-hortagga burada iyadoo nidaamisa apoptosis-ka unugga, ka hortagga faafinta iyo soo-galitaanka unugyada burooyinka, iyo nidaaminta waddooyinka calaamadaynta unugyada kansarka.
- Saamaynta Hypoglycemic:Ursolic acid waxay saameyn gaar ah ku leedahay hoos u dhigista sonkorta dhiigga iyo hagaajinta shaqada unugga gasiirada ee ganaca. Waxay kor u qaadaa dheecaanka insulinta waxayna wanaajisaa dareenka insulinta, si ay u caawiso maaraynta cudurka macaanka iyo ka hortagga dhibaatooyinka la xiriira.
- Dhaqdhaqaaqa bakteeriyada iyo fayraska:Ursolic acid waxay leedahay hawlo bakteeriyada iyo fayraska qaarkood oo ka dhan ah bakteeriyada iyo fayrasyada kala duwan. Waxay joojisaa koritaanka iyo taranka bakteeriyada iyo fayrasyada, yaraynta khatarta caabuqa iyo cudurrada.
Intaa waxaa dheer, ursolic acid ayaa la ogaaday inay leedahay ilaalinta maqaarka, sifooyinka antioxidant, iyo iska caabinta cudurrada wadnaha ischaemic.
