Nri Nri Nri Ọkwa Oleanolic Acid ntụ ntụ
Kedu ihe bụ oleanolic acid?
Oleanolic acid (OA), a eke hydroxyl pentacyclic triterpenoid acid (HPTA) yiri betulinic acid, ursolic acid;
Ebee ka ị ga-ahụ oleanolic acid?
Ụfọdụ mkpụrụ osisi dị ka apụl, pọmigranet, lemon, bilberries, olive nwere oleanolic acid.
| Aha ogwu | Oleanolic acid ọdịnaya | Usoro ule |
| Onye privet na-egbuke egbuke kwuru | 0.8028% | HPLC |
| Verbena Officinalis L | 0.071% -0.086% | HPLC |
| Prunella vulgaris L | 3.47% -4.46% | HPLC |
| Hemsley Chinensis Cogn. | 1.5% ~ 2% | HPLC |
Ugbu a, Chinese ahịhịaHemsley Chinensis Cognka bụ ngwa ahịa kacha ere maka ịwepụta oleanolic acid.
Hemsley Chinensis Cogn.Okwu mmalite
Hemsleya chinensis Cogn.bụ ahịhịa na-arị elu perennial, bụkwa ọgwụ ọdịnala ndị China.
- Ezinụlọ: Cucurbitaceae
- Agbụrụ: Gomphogyneae
- Genus: Hemsleya
- Ụdị: H. ọmarịcha
A na-ekesa ahịhịa a na mpaghara Guangxi, Sichuan, Guizhou, Yunnan, Hubei, wdg. Amụrụ na nsọtụ oke ọhịa na osisi ndagwurugwu n'ogo dị ihe dị ka mita 2,000.
Ihe na-arụ ọrụ: nwere Hemslolide Mal, Ma3, H1; Chikusetsusaponin-Iva; dihydro cucurbitacin F-25-acetate; dilydrocucurbitacin F; oleanolic acid - beta-Hlucosyloleanolate; Hemsamabilinin A; Cu-curbitacin Ⅱb-2-beta-D-glucopyranoside.
Mwepụta nke Oleanolic acid na Hemsleya Chinensis Cogn.
Ntụle bụ isi
| Ihe nyocha | Nkọwapụta | Nsonaazụ | Ụzọ ule |
| Nyocha | ≥98.0% | 98.4% | HPLC |
| Organoleptic | |||
| Ọdịdị | Ntụ ntụ | Kwado | Organoleptic |
| Agba | Na-acha ọcha crystalline ntụ ntụ | Kwado | Organoleptic |
| Isi | Enweghị isi na enweghị ụtọ | Kwado | Organoleptic |
| Njirimara anụ ahụ | |||
| Ọnwụ na ihicha | ≤0.5% | 0.01% | USP |
| Ihe fọdụrụ | ≤0.1% | 0.039% | USP |
| Ntughari pụrụ iche | 75.0°-83.0° | 78.2° | CP2010 |
| Ọla dị arọ | |||
| Mgbakọta ọla dị arọ | 20ppm Max | Kwado | USP Usoro II |
| Ndu (Pb) | 3pm NMT | Kwado | ICP-MS |
| Arsenic (dị ka) | 2pm NMT | Kwado | ICP-MS |
| Cadmium (Cd) | 1pm NMT | Kwado | ICP-MS |
| Mercury (Hg) | 0.1pm NMT | Kwado | ICP-MS |
| Nnwale Microbiological | |||
| Ngụkọta ọnụ ọgụgụ efere: | NMT 5,000 cfu/g | Kwado | AOAC |
| Yist & ebu: | NMT 300 cfu/g | Kwado | AOAC |
| Salmonella: | Ihe ọjọọ | Kwado | AOAC |
| E.Coli: | Ihe ọjọọ | Kwado | AOAC |
Ọrụ
Oleanolic acid (ursolic acid) bụ eke triterpenoid onyinye nke a na-ahụkarị na osisi, dị ka bearberry, oliv, blueberries, wdg. Nke a bụ ụfọdụ ndị ọkachamara iwebata Oleanolic Acid:
- Mmetụta mgbochi mkpali na antioxidant:Ursolic acid nwere mmetụta mgbochi mkpali na mgbochi mkpali. Ọ nwere ike ibelata mmeghachi omume mkpali, gbochie ntọhapụ nke ndị mgbasa ozi na-egbuke egbuke, wepụ ihe ndị na-akpata free radicals n'ime ahụ, ma belata mmebi nke nrụgide oxidative kpatara.
- Nchedo imeju:Ursolic acid nwere mmetụta nchebe na imeju. Ọ na-akwalite mmepụta imeju na imeju, na-ebelata ihe ize ndụ nke mmebi imeju. Ursolic acid nwekwara ike igbochi ma gwọọ ọrịa imeju dị ka imeju abụba abụba site na ịhazi metabolism abụba na imeju.
- Ọrụ mgbochi tumor:Ursolic acid nwere mmetụta mgbochi na ụfọdụ mkpụrụ ndụ tumo. Ọ nwere ike rụọ ọrụ mgbochi tumo site n'ịchịkwa apoptosis cell, na-egbochi mmụba na mbuso agha nke mkpụrụ ndụ tumo, na ịhazi ụzọ mgbaàmà nke mkpụrụ ndụ kansa.
- Mmetụta hypoglycemic:Ursolic acid nwere mmetụta ụfọdụ na mbelata shuga ọbara na imeziwanye ọrụ sel sel pancreatic. Ọ na-akwalite mmepụta insulin ma na-eme ka mmetụta insulin dịkwuo mma, si otú a na-enyere aka ịchịkwa ọrịa shuga ma gbochie nsogbu ndị metụtara ya.
- Antibacterial na antiviral ọrụ:Ursolic acid nwere ụfọdụ ọrụ antibacterial na antiviral megide nje bacteria na nje dị iche iche. Ọ na-egbochi uto na mmụgharị nke nje bacteria na nje, na-ebelata ohere nke ibute ọrịa na ọrịa.
Na mgbakwunye, achọpụtara na ursolic acid nwere ihe nchebe akpụkpọ anụ, ihe antioxidant, na iguzogide ọrịa obi ischemic.
