Iyini i-rutin?
I-Rutin i-pigment yesitshalo etholakala ezithelweni ezithile nemifino. I-Buckwheat, isihlahla se-pagoda saseJapane, ne-Eucalyptus yimithombo ye-rutin.
I-Rutin nayo itholakala ezimbalini zesihlahla se-lime, izimbali ezindala, i-hawthorn, i-rue, i-St. John's Wort, i-Ginkgo, ama-apula, nezinye izithelo nemifino. I-Rutin ingaba nemiphumela ye-antioxidant ne-anti-inflammatory. Ingase futhi inikeze isivikelo esithile kumdlavuza nezinye izifo.
I-Rutin ijwayele ukusetshenziselwa i-autism, isikhumba esiguga, izifo zendlela yomoya ezibangelwa ukuzivocavoca, nezinye izinjongo eziningi, kodwa abukho ubufakazi obuhle besayensi obusekela noma yikuphi kwalokhu kusetshenziswa.
Izinzuzo Zezempilo
- Ithuthukisa Impilo Yenhliziyo
Uma kukhulunywa ngempilo yenhliziyo yakho, ucwaningo lwakamuva lubonisa ukuthi i-rutin ingasiza ekugcineni ukunwebeka kwemithambo yegazi, inciphise ukuqina kwemithambo yegazi, i-capillary permeability ephansi futhi ivimbele izinkinga ezibangelwa umfutho wegazi ophakeme.
Ucwaningo lwezilwane lwango-2018 olushicilelwe ku-Experimental and Therapeutic Medicine lwathola ukuthi luvimbela isifo senhliziyo ngokusayina i-protein kinases ethile ebizwa ngokuthi i-ERK1/2 ne-Akt. Umthamo we-rutin osebenza kahle kakhulu owawusetshenziswa ezingulubeni ezinesifo senhliziyo wawungamamiligremu angu-45 ngekhilogremu ngayinye yesisindo somzimba. Ukuphathwa kwe-Rutin kusebenze ukunciphisa usayizi wezicubu ezifile enhliziyweni yezingulube ezinesifo senhliziyo, ukuvimbela ukugcwala kwamaprotheni omchamo kanye nokujikeleza kwegazi okuthuthukisiwe.
Olunye ucwaningo lwezilwane lwango-2014 olushicilelwe ku-Human & Experimental Toxicology lwathola ukuthi ukwelashwa nge-rutin ne-quercetin kunciphisa imiphumela yenhliziyo nemithambo yegazi yokudla okunosawoti omningi kumagundane we-hypertensive. Eqinisweni, inhlanganisela yalezi bioflavonoid yayisebenza kangcono kunokwelashwa nge-nifedipin, umuthi osetshenziselwa ukwelapha umfutho wegazi ophakeme kanye nobuhlungu besifuba.
- Ikhulula Izimpawu Zesifo Samathambo
Ucwaningo lwezilwane lubonisa ukuthi le antioxidant inamandla okuvimbela ukuvuvukala okunamandla nokungapheli. Lokho kwenza kube ukwelashwa okungokwemvelo kwe-arthritis. Abacwaningi baseRussia bathola ukuthi i-rutin ikwazile ukunciphisa ukukhiqizwa ngokweqile kwama-radicals mahhala ku-rheumatoid arthritis. Baphethe ngokuthi ingathathwa njenge-ejenti esekelayo yemithi ewusizo.
Ukwengeza, ucwaningo lwelebhu lwango-2017 olushicilelwe ku-Pharmacology lwathola ukuthi i-rutin ithuthukise ukwakheka kwezicubu phezu kwendawo ehlangene, ithuthukise uqwanga nokuguguleka kwamathambo, nokunciphisa ukuvuvukala. Lokhu kusikisela ukuthi inomphumela wokuvikela ngokumelene nesifo samathambo.
- Ulwa Nomdlavuza
I-Rutin ingase isebenze njenge-ejenti yokwelapha yokulwa nomdlavuza ngenxa yemiphumela yayo ye-antioxidant ne-anti-inflammatory. Kuphinde kukhonjiswe ukuthi kudala i-apoptosis, noma ukufa kweseli lomdlavuza, futhi kubonise imiphumela elwa nesimila. Ama-Flavonoid asetshenziselwe ukuqwashisa amangqamuzana omdlavuza emithini elwa nomdlavuza futhi ahlehlise ukumelana nezidakamizwa ezigulini ezelashwa umdlavuza.
Kunocwaningo oluningi olubandakanya abantu, amagundane namaseli okuphakamisa ukuthi le antioxidant isebenza ukunciphisa usayizi wesimila, yandise ukufa kwamangqamuzana omdlavuza futhi yandise isikhathi sokusinda. Ukubuyekezwa kwesayensi okudingida amandla ekhemisi e-rutin kutholwe ukuthi i-flavonoid ibonise imiphumela yokulwa nomdlavuza ngokumelene nenani lezinhlobo zomdlavuza, okuhlanganisa i-leukemia, umdlavuza wekoloni, umdlavuza we-colorectal, i-melanoma, umdlavuza wesibindi nomdlavuza wamaphaphu.
Ucwaningo lwelebhu olushicilelwe ku-Phytotherapy Research luthole ukuthi le phytochemical isebenza njenge-chemosensitizer emigqeni emibili yamangqamuzana omdlavuza webele womuntu. I-Rutin yandisa kakhulu umsebenzi wokulwa nomdlavuza wezidakamizwa ezisetshenziselwa ukulwa nomdlavuza futhi yasiza ngempumelelo ukumisa ukuqhubeka komjikelezo wamaseli.
Olunye ucwaningo ngelebhu olwanyatheliswa kuyi-Scientific World Journal lwathola ukuthi i-rutin isiza ukulwa ne-neuroblastoma, uhlobo lomdlavuza oluvame ukutholakala ezindlala ze-adrenal zezingane. Yakha i-apoptosis yamaseli futhi yalawula ukubonakaliswa kwezakhi zofuzo ezihlobene ne-apoptosis.
- Ivikela Ezifweni Ze-Metabolic
Ucwaningo lubonisa ukuthi i-rutin ingasivikela ekuthuthukiseni i-metabolic syndrome njengoba sikhula. Ucwaningo olubandakanya amagundane asebekhulile lwathola ukuthi i-flavonoid ivimbele ukwanda kweglucose yegazi, amazinga e-insulin nomfutho wegazi.
Ukuphathwa kwe-Rutin kuthuthukise ukungasebenzi kahle kwe-metabolic ehlobene nokuguga kumagundane ngokunciphisa ukuvuvukala, ukunqwabelana kwamafutha, ukucindezeleka kwe-oxidative kanye nesifo se-mitochondrial, ukuphazamiseka okubangelwa ukwehluleka kwe-mitochondria etholakala cishe kuwo wonke amangqamuzana omzimba womuntu.
- Ivikela Impilo Yengqondo
Ucwaningo lubonisa ukuthi i-rutin inemiphumela yokuzivikela ekulimaleni kobuchopho nokulimala okuhlobene neminyaka. Kuyasiza futhi ukukhuthaza impilo yobuchopho ngenxa yezakhiwo zayo zokulwa nokuvuvukala kanye ne-antioxidant.
Ngo-2018, ucwaningo olwanyatheliswa ku-Oxidative Medicine and Cellular Longevity luphakamisa ukuthi le bioflavonoid isebenza njengenhlanganisela ethembisayo ye-neuroprotective yokwelapha izifo ze-neurodeergenerative, okuhlanganisa nesifo i-Alzheimer's, isifo sika-Parkinson nesifo sika-Huntington. Abacwaningi bakholelwa ukuthi ivikela impilo yobuchopho ngokunciphisa ama-cytokines ane-pro-inflammatory, ukuthuthukisa imisebenzi ye-enzyme ye-antioxidant nokubuyisela imisebenzi yama-enzyme e-mitochondrial eyinkimbinkimbi ngaphakathi kwamaseli ethu.
- Ivimba Amahlule Egazi
Abaphenyi base-Beth Israel Deaconess Medical Center esebenzisana ne-Harvard bathole ukuthi i-rutin ingase isebenze njengesu elisha lokuvimbela i-thrombosis kumamodeli ezilwane. I-Thrombosis yilapho ihlule legazi lakheka emithanjeni noma emthanjeni. I-Deep vein thrombosis iyingozi kakhulu ngoba ingabangela izinkinga ezisongela ukuphila, njengokushaywa unhlangothi nokuhlasela kwenhliziyo.
Abacwaningi bathola ukuthi i-rutin inhibits protein disulfide isomerase (PDI), ekhishwa ngokushesha kumaplatelet ethu namaseli endothelial ngesikhathi se-thrombosis. Ngokuvimbela ukugcinwa kwe-PDI, i-antioxidant yafakazela ukuthi ivimbela i-thrombosis kumagundane.
Ayivimbeli i-PDI kuphela, kodwa futhi ivimbela inhlanganisela ukuthi ingangeni kumaseli. Abacwaningi bathole ukuthi kusize ukuvimbela amahlule egazi kuyo yomibili imithambo yegundane kanye nemithambo, futhi kuthiwa iyona kuphela into engavimba zombili izinhlobo zamahlule.
- Ithuthukisa Ukujikeleza
Emithi yesintu, i-rutin yaziwa ngamandla ayo okuqinisa imithambo yegazi nokuthuthukisa ukujikeleza kwegazi. Isetshenziselwa ukunciphisa ukubonakala kwemithambo ye-varicose, ukukhulula ama-hemorrhoids nokuvimbela imivimbo eyophayo ebangelwa imithambo ephukile noma imithambo.
Ukubuyekezwa okushicilelwe kuyi-International Journal of Molecular Sciences kubonisa ukuthi amalungiselelo e-rutin abikwa ukuthi anciphisa kakhulu ukuvuvukala komlenze, akhulule ubuhlungu bomlenze, futhi anciphise amajaqamba emilenzeni, ubunzima kanye nokuluma. Lokhu kungenzeka ngenxa yekhono layo lokunciphisa ukuvuvukala nokuthuthukisa ukujikeleza kwegazi.
Okuhlobene: I-Fisetin: I-Senolytic Antioxidant yokuguga Okunempilo nokuningi
Ukudla okuphezulu kwe-Rutin okungu-20
I-Rutin iyi-flavonoid etholakala ekudleni okuningi nasezitshalweni, kuhlanganise nezithelo ezisawolintshi, ama-apula kanye ne-buckwheat. Indlela engcono kakhulu yokuwufaka ekudleni kwakho ukudla ukudla okuphezulu kule antioxidant ethile.
I-Rutin ingesinye sezakhi ezisebenzayo kulokhu kudla nezitshalo ezilandelayo:
Izincomo Zesengezo kanye Nemithamo
I-Rutin itholakala njengesengezo ekudleni okuningi kwezempilo noma ezitolo zamavithamini. Ungathola umkhiqizo oqukethe i-rutin kuphela noma owodwa oqukethe ingxube ye-bioflavonoid, njenge-bioflavonoid complex. Ngenxa yalesi sizathu, inani lale flavonoid ethile emkhiqizweni liyahlukahluka kakhulu.
Uzothola ukuthi izithasiselo eziningi ze-rutin emakethe namuhla ziqukethe ama-milligrams angama-500 i-capsule ngayinye. Asikho isilinganiso esicacile se-rutin esinconywayo, esinemithamo esukela kumamiligremu angama-500 ngosuku kuya kumagremu amane ngosuku.
Olunye ucwaningo lubonisa ukuthi ukuthatha amagremu amane ngomlomo ngosuku kuwumthamo ophumelelayo futhi obekezelelwe kahle. Kodwa-ke, lokhu kuphakeme kakhulu kunomthamo ojwayelekile onconyiwe emikhiqizweni engeziwe, ngakho thintana nomhlinzeki wakho wokunakekelwa kwezempilo ngaphambi kokuthatha imithamo emikhulu.
Isikhathi sokuthumela: Aug-15-2023
