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Mwepụta osikapa yist na-acha uhie uhie bụ ngwaahịa sitere na osikapa indica nke agbagoro na ebu uhie Monascus purpureus.Ọ na-ewu ewu na China, ebe ejirila ya mee ihe kemgbe ọtụtụ narị afọ dị ka nri na ọgwụ.
Mwepụta osikapa yist na-acha uhie uhie bụ ihe na-ewu ewu n'ọtụtụ efere ndị China.Dịka ọmụmaatụ, ọ bụ ihe mgbakwunye nri na ọbọgwụ a ṅara n'ọkụ Beijing, ham, ihe ọṅụṅụ, na ihe ndị ọzọ.A na-ejikwa ihe mgbako osikapa yist na-acha uhie uhie na-eme ihe ịchọ mma na ngwaahịa nlekọta anụ ahụ na ihe mkpuchi maka ụmụ nwanyị dị ime.Na mgbakwunye, a na-eme ha ka ọ bụrụ mgbakwunye nri iji belata ọkwa cholesterol ọbara na lipids ndị metụtara ya.CIMA na-enyekarị mpụta osikapa yist na-arụ ọrụ.
Osikapa yist na-acha uhie uhie ọ bụ ọgwụ ma ọ bụ mgbakwunye nri?
Azịza ya, dị mgbagwoju anya, bụ ha abụọ.Monacolin K bụ ihe kachasị mkpa na mpụta osikapa yist na-acha uhie uhie, nke na-enyere aka belata cholesterol.
Ihe mejupụtara ihe mkpofu osikapa yist na-acha uhie uhie
Ihe karịrị ihe mejupụtara kemịkalụ 101 dịpụrụ adịpụ na osikapa yist na-acha ọbara ọbara, gụnyere monacolin, pigmenti, organic acid, sterol, naphthalene derivatives, flavonoids, polysaccharides, na ndị ọzọ.
Ngwaahịa osikapa yist na-acha uhie uhie na-arụ ọrụ nwere ihe a na-akpọ Monacolin K, na monacolin K nke anụ ahụ karịrị 0.4% osikapa yist na-acha uhie uhie.Nke a bụ statin kasị dị irè na-eme n'okike dị ugbu a.Dị ka ọtụtụ statins, ọ na-ebelata ọkwa cholesterol n'ime ọbara site na ibelata oke cholesterol nke imeju na-emepụta.Dị ka ọtụtụ statins, ọ na-ebelata ọkwa cholesterol n'ime ọbara site na ibelata oke cholesterol nke imeju na-emepụta.
Ụdị osikapa yist na-acha uhie uhie na nkọwapụta
Aogubio na-enye ntụ ntụ osikapa yist na-acha uhie uhie na granules na nkọwa nke 0.4%, 1%, 1.5%, 3%, 4%, 5%.
Monacolin k Okwu mmalite
Monacolin K dị n'ụdị abụọ: ụdị lactone mechiri emechi (nọmba A) na ụdị acid mepere emepe (nọmba B).
Lactone monacolin K kwụsiri ike karịa ụdị acid.Monacolin K na-agbanwe site na acid gaa na lactone na gburugburu acidic.Monacline K nke ụdị lactone bụ obere mmiri soluble karịa monacline K nke ụdị acid, ọ dịkwa mfe kristal ma ọ bụ wụsa.Nbibi nke Monacolin K sitere na kpo oku, ma enwere obere ọdịiche dị n'etiti mmebi acid na lactone monacolin K.Ìhè na-eme ka ire ere nke Monaclin K. Acidic Monaclink yiri ya na HMG-COA reductase na ahụ mmadụ ma mepụta usoro asọmpi na ya iji gbochie njikọ cholesterol n'ime ahụ mmadụ.Lactone monaclin K chọrọ njikọ nke hydroxyesterase n'ime ahụ mmadụ iji gbochie njikọ cholesterol.Enwere ọdịiche dị n'etiti ndị mmadụ n'otu n'otu na ikike ha nwere ịmepụta hydroxyl esterase dị iche, ya mere acid monacline K dị mma karịa lactone monacline K n'ime ahụ mmadụ.
Monacolin K VS Lovastatin
Monacolin K adịghị ka lovastatin.Monaclink na-abịa n'ụdị abụọ, lactone, na acid.Ụdị lactone nke monacolin K na lovastatin bụ otu kemịkalụ.Lovastatin bụ ihe na-arụ ọrụ n'ọtụtụ ọgwụ ndị European Union kwadoro iji gwọọ hypercholesterolemia.
Monacolin K na lovastatin na-agbanwe ngwa ngwa site na lactone ha gaa n'ụdị hydroxy acid (HA), nke ikpeazụ bụ maka igbochi HMG-CoA reductase enzyme na-etinye aka na biosynthesis nke cholesterol.Ọ bụ ezie na ụdị acidic na-apụtakarị na RYR, n'ihe banyere lovastatin, ọgbọ ya chọrọ ntụgharị site na ụdị lactone.
Osikapa yist na-acha uhie uhie na coq10
Osikapa yist na-acha uhie uhie na-enwekarị ogige ndị yiri nke a na-ahụ na ọgwụ statin, nke a na-enyekarị iji gwọọ cholesterol dị elu.Statins nwere ike igbochi ọkwa Coenzyme Q10 (CoQ10), ihe na-edozi ahụ dị mkpa maka ahụike obi na akwara.Ọkwa dị ala nwekwara ike ime ka mgbaàmà ndị metụtara ọgwụgwọ ndị a ka njọ.N'ihi myirịta ha, ụfọdụ nchegbu dị na osikapa yist na-acha ọbara ọbara nwekwara ike gbanwee ọkwa CoQ10, dabere na Mahadum Medical Center nke Maryland.
Usoro nrụpụta osikapa yist na-acha uhie uhie
Sterilisization, usoro omenala mkpụrụ, ịgbako osikapa yist na-acha uhie uhie, ihicha bụ isi ihe njikwa mma:
- Sterilisation: sterilization na 121 degrees maka nkeji 20
- Usoro omenala mkpụrụ: achọrọ omenala mkpụrụ dị ọcha, na okpomọkụ dị ogo 30, oge omenala bụ awa 48.
- Fermentation nke osikapa yist na-acha uhie uhie: okpomọkụ 30 degrees, iru mmiri 60-90%, iji gbochie nje bacteria dị iche iche na usoro ịgba ụka.
- ihicha: oge bụ awa 12-14, na okpomọkụ bụ 110 degrees.
Uru ahụike nke mpụta osikapa yist na-acha uhie uhie
- Enyemaka maka High Cholesterol
Ihe mgbakwunye anụ ahụ na-acha uhie uhie yist ka egosiri na ọ na-ebelata lipids ọbara dị elu na ọkwa cholesterol.Ingredient Monascus (Monas) nwere ike igbochi enzyme nke na-enyere aka ịmepụta ogige nwere ike imerụ ahụ nke a maara dị ka LDL cholesterol ma n'otu oge ahụ na-akwalite HDL dị mma na ahụ gị.Nnyocha na-egosi na mwepụta a naanị ma ọ bụ ihe mgbakwunye ndị ọzọ na-eme ka ahụike zuru oke maka ndị dara n'okpuru 140 mg / dL na ule ha.
- Enyemaka na osteoporosis syndrome
Ndị ọkà mmụta sayensị chọtara ihe a na-akpọ ergosterol na osikapa yist na-acha uhie uhie, ihe na-ebute vitamin D2 na-agbaze abụba, bụ nke a na-atụgharị na vitamin D2 n'okpuru radieshon ultraviolet.A maara vitamin D2 na-akwalite nnabata nke calcium na phosphorus.
- Nyere aka belata ọbara mgbali
A na-eme nchọpụta na mmewere GABA dị na broth nke osikapa yist na-agba agba, ma nwee ike inye aka belata ọbara mgbali.
- Mgbochi ọrịa cancer na Chebe akụrụ
Monacolin K nwere ike belata mitotic index nke mkpụrụ ndụ kansa na ọrụ nke Na +-K+-ATP enzyme, ma gbochie uto mkpụrụ ndụ kansa.Ọmụmụ ọgwụ egosila na Monacolin K nwere nnukwu mgbochi nke mgbasa mkpụrụ ndụ mesangial na nzuzo nzuzo matrix extracellular.Ya mere o nwere ọrụ nke ichebe akụrụ.
Nchekwa nke Mwepụta Osikapa yist na-acha uhie uhie
- Ọnụ ọgụgụ dị elu nke ụdị acid Monacolin k, nke nwere mmetụta dị ntakịrị karịa ụdị lactone.Ụdị acid VS lactone bụ 80:20,
- Citrinin n'efu
- Igwe ọkụ n'efu
- 100% siri ike gbaa ụka, nke na-eme ka mmetọ nje dị obere.
Ngwa nke Mwepụta osikapa yist na-arụ ọrụ
- Dị ka ihe mgbakwunye nke ihe mgbakwunye nri na nri ahụike iji belata cholesterol, ụfọdụ ngwaahịa mgbakwunye na-ejikwa ya na ihe ndị ọzọ, dịka ọmụmaatụ, ngwaahịa na-echebe ọkpụkpụ na-ejikọta mpụta osikapa yist na-acha uhie uhie na calcium organic acid;Ọrịa Menopausal na-agwọ ngwaahịa na-ejikọta mpụta osikapa yist na-acha uhie uhie na hormone osisi.
– Medical ojiji.
