Icyitegererezo cyubusa cyiza cyumusemburo utukura
Umusemburo utukura wumuceri ni iki?
Umusemburo utukura wumuceri nigicuruzwa gisanzwe gikozwe mumuceri wa indica wasizwe hamwe na pisine itukura Monascus purpureus.Irazwi cyane mu Bushinwa, aho imaze ibinyejana byinshi ikoreshwa nk'ibiryo n'ubuvuzi.
Umusemburo utukura wumuceri ni ikintu kizwi cyane mubiryo byinshi byabashinwa.Kurugero, ninyongera ibiryo muri Beijing inkongoro ikaranze, ham, umutobe, nibindi.Ibicuruzwa bivamo umuceri utukura bikoreshwa no kwisiga no gutunganya uruhu muri kondereti ku bagore batwite.Byongeye kandi, bikozwe mubyokurya kugirango bagabanye amaraso ya cholesterol hamwe na lipide bifitanye isano.CIMA itanga cyane cyane umusemburo utukura wumuceri utukura.
Umuceri utukura Umuceri ukuramo ibiyobyabwenge cyangwa inyongeramusaruro?
Igisubizo, giteye urujijo, ni byombi.Monacolin K ningirakamaro cyane mubisarurwa byumuceri utukura, bifasha kugabanya cholesterol.
Ibigize umusemburo utukura
Ibigize imiti irenga 101 bitandukanijwe numuceri utukura, harimo monacoline, pigment, aside organic, sterol, ibikomoka kuri naphthalene, flavonoide, polysaccharide, nibindi.
Umusemburo utukura wumuceri utukura urimo ibintu byitwa Monacolin K, naho monacolin K isanzwe irenze 0.4% yumuceri utukura.Nibikorwa byiza bisanzwe bibaho statin irahari.Kimwe na statine nyinshi, igabanya urugero rwa cholesterol mu maraso igabanya urugero rwa cholesterol ikorwa n'umwijima.Kimwe na statine nyinshi, igabanya urugero rwa cholesterol mu maraso igabanya urugero rwa cholesterol ikorwa n'umwijima.
Imiterere yumuceri wumuceri nuburyo bwihariye
Aogubio itanga ifu yumuceri wumuceri na granules mubisobanuro bya 0.4%, 1%, 1.5%, 3%, 4%, 5%.
Monacolin k Intangiriro
Monacolin K ibaho muburyo bubiri: ubwoko bwa lactone ifunze (ishusho A) nubwoko bwa acide ifunguye (ishusho B).
Lactone monacolin K yari ihagaze neza kuruta ubwoko bwa aside.Monacolin K ihinduka kuva aside ikajya kuri lactone mubidukikije.Monacline K yo mu bwoko bwa lactone ntishobora gukama amazi kurusha monacline K y'ubwoko bwa aside, kandi biroroshye gutobora cyangwa kugwa.Kwangirika kwa Monacolin K kwatewe no gushyushya, kandi hari itandukaniro rito hagati ya aside na lactone monacolin K iyangirika.Umucyo ukomeza kwangirika kwa Monaclin K. Acidic Monaclink isa cyane mumiterere na HMG-COA reductase mumubiri wumuntu kandi ikora uburyo bwo guhatana nayo kugirango ibuze neza synthesis ya cholesterol mumubiri wumuntu.Lactone monaclin K isaba guhuza hydroxyesterase mumubiri wumuntu kugirango ibuze synthesis ya cholesterol.Hariho itandukaniro hagati yabantu nubushobozi bwabo bwo gukora hydroxyl esterase iratandukanye, so monacline K iruta K lactone monacline K mumubiri wumuntu.
Monacolin K VS Lovastatin
Monacolin K ntabwo isa na lovastatin.Monaclink ije muburyo bubiri, lactone, na aside.Imiterere ya lactone ya monacolin K na lovastatin ni imiti imwe.Lovastatin ni ingirakamaro mu miti myinshi yemejwe n’umuryango w’ubumwe bw’ibihugu by’Uburayi kuvura hypercholesterolemia.
Monacolin K na lovastatin bihindurwa byihuse biva muri lactone bihinduka aside hydroxy imwe (HA), iyanyuma ikaba ifite inshingano zo kubuza enzyme ya HMG-CoA reductase igira uruhare muri biosynthesis ya cholesterol.Mugihe imiterere ya acide isanzwe iboneka muri RYR, kubijyanye na lovastatine, ibisekuruza byayo bisaba guhinduka muburyo bwa lactone.
Umuceri utukura hamwe na coq10
Umuceri utukura usanzwe urimo ibintu bisa nibiboneka mu miti ya statin, bikunze gutegekwa kuvura cholesterol nyinshi.Sitati irashobora kubangamira urwego rwa Coenzyme Q10 (CoQ10), intungamubiri zingenzi kumagara no mumitsi.Urwego rwo hasi rushobora kandi kongera ibimenyetso byihariye bijyanye nubuvuzi.Kubera guhuza kwabo, hari impungenge zibaho ko umuceri wumusemburo utukura ushobora no guhindura urwego rwa CoQ10, rushingiye ku kigo nderabuzima cya kaminuza ya Maryland.
Umusemburo utukura umuceri
Kurimbuka, umuco wimbuto uringaniye, umusemburo utukura wumuceri fermentation, gukama nibintu byingenzi bigenzura ubuziranenge:
- Sterilisation: sterilisation kuri dogere 121 muminota 20
- Umuco wimbuto uringaniye: umuco wimbuto urasabwa, kandi ubushyuhe ni dogere 30, naho umuco ni amasaha 48.
- Gusembura umuceri utukura: ubushyuhe bwa dogere 30, ubuhehere 60-90%, kugirango wirinde kwanduza bagiteri zitandukanye mugikorwa cya fermentation.
- Kuma: igihe ni amasaha 12-14, n'ubushyuhe ni dogere 110.
Inyungu zubuzima bwumusemburo utukura
- Ubufasha bwa Cholesterol
Umuceri usanzwe wumuceri utukura byagaragaye ko ugabanya lipide nyinshi mumaraso hamwe na cholesterol.Ibigize Monascus (Monas) birashobora guhagarika enzyme ifasha gukora ibice bishobora kwangiza bizwi nka LDL cholesterol mugihe kimwe no guteza imbere HDL zifite ubuzima bwiza mumubiri wawe.Ubushakashatsi bwerekana iki gice cyonyine cyangwa hamwe nibindi byongeweho bizamura ubuzima muri rusange kubamanutse munsi ya 140 mg / dL kubizamini byabo.
- Gufasha hamwe na syndrome ya osteoporose
Abahanga mu bya siyansi bavumbuye ikintu cyitwa ergosterol mu musemburo w’umuceri utukura, kibanziriza vitamine D2 ikuramo amavuta, hanyuma igahinduka vitamine D2 ikoresheje imirasire ya ultraviolet.Vitamine D2 izwiho guteza imbere kwinjiza calcium na fosifore.
- Fasha kugabanya umuvuduko wamaraso
Ubushakashatsi bwakozwe bwerekana ko ikintu GABA kibaho mu musemburo wa fermentation yumuceri utukura, kandi ushobora gufasha kugabanya umuvuduko wamaraso.
- Kurwanya Kanseri no Kurinda impyiko
Monacolin K irashobora kugabanya indangagaciro ya selile ya kanseri nibikorwa bya enzyme ya Na + -K + -ATP, ikanabuza gukura kwa selile.Ubushakashatsi bwa farumasi bwerekanye ko Monacolin K ifite uburyo bubuza ikwirakwizwa rya selile ya mesangial no gusohora matrix idasanzwe.Ifite rero umurimo wo kurinda impyiko.
Umutekano wumusemburo utukura wumuceri
- Umubare munini wa acide ya Monacolin k, ifite ingaruka nke ugereranije na lactone.Ifishi ya acide Ifishi ya lactone ni 80:20,
- Citrinin kubuntu
- Irrasiyo Yubusa
- 100% Fermentation ikomeye, ituma bagiteri zandura nke.
Gushyira mu bikorwa Umusemburo Utukura Umuceri Umuceri
- Nka nyongeramusaruro yinyongera nibiryo byubuzima kugirango cholesterol igabanuke, nanone bimwe mubicuruzwa byiyongera nabyo birabikoresha kugirango bihuze nibindi bikoresho, urugero, ibicuruzwa birinda amagufwa bihuza umusemburo wumuceri utukura hamwe na calcium ya aside aside;Indwara ya Menopausal ivura ibicuruzwa bivanga umusemburo utukura wumuceri na hormone yibimera.
- Gukoresha ubuvuzi.
